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Page 1
Evaluation of C-5 propynyl pyrimidine-containing oligonucleotides in vitro and in vivo.
Shen L, Siwkowski A, Wancewicz EV, Lesnik E, Butler M, Witchell D, Vasquez G, Ross B, Acevedo O, Inamati G, Sasmor H, Manoharan M, Monia BP. Shen L, et al. Among authors: monia bp. Antisense Nucleic Acid Drug Dev. 2003;13(3):129-42. doi: 10.1089/108729003768247592. Antisense Nucleic Acid Drug Dev. 2003. PMID: 12954113
Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice.
Prakash TP, Graham MJ, Yu J, Carty R, Low A, Chappell A, Schmidt K, Zhao C, Aghajan M, Murray HF, Riney S, Booten SL, Murray SF, Gaus H, Crosby J, Lima WF, Guo S, Monia BP, Swayze EE, Seth PP. Prakash TP, et al. Among authors: monia bp. Nucleic Acids Res. 2014 Jul;42(13):8796-807. doi: 10.1093/nar/gku531. Epub 2014 Jul 3. Nucleic Acids Res. 2014. PMID: 24992960 Free PMC article.
Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid.
Albertshofer K, Siwkowski AM, Wancewicz EV, Esau CC, Watanabe T, Nishihara KC, Kinberger GA, Malik L, Eldrup AB, Manoharan M, Geary RS, Monia BP, Swayze EE, Griffey RH, Bennett CF, Maier MA. Albertshofer K, et al. Among authors: monia bp. J Med Chem. 2005 Oct 20;48(21):6741-9. doi: 10.1021/jm050490b. J Med Chem. 2005. PMID: 16220989
miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting.
Esau C, Davis S, Murray SF, Yu XX, Pandey SK, Pear M, Watts L, Booten SL, Graham M, McKay R, Subramaniam A, Propp S, Lollo BA, Freier S, Bennett CF, Bhanot S, Monia BP. Esau C, et al. Among authors: monia bp. Cell Metab. 2006 Feb;3(2):87-98. doi: 10.1016/j.cmet.2006.01.005. Cell Metab. 2006. PMID: 16459310 Free article.
Peptide nucleic acids conjugated to short basic peptides show improved pharmacokinetics and antisense activity in adipose tissue.
Wancewicz EV, Maier MA, Siwkowski AM, Albertshofer K, Winger TM, Berdeja A, Gaus H, Vickers TA, Bennett CF, Monia BP, Griffey RH, Nulf CJ, Hu J, Corey DR, Swayze EE, Kinberger GA. Wancewicz EV, et al. Among authors: monia bp. J Med Chem. 2010 May 27;53(10):3919-26. doi: 10.1021/jm901489k. J Med Chem. 2010. PMID: 20420385 Free PMC article.
243 results