Lu ZL - Search Results

1

Molecular genetic analysis of normosmic hypogonadotropic hypogonadism in a Turkish population: identification and detailed functional characterization of a novel mutation in the gonadotropin-releasing hormone receptor gene.

Topaloglu AK, Lu ZL, Farooqi IS, Mungan NO, Yuksel B, O'Rahilly S, Millar RP. Topaloglu AK, et al. Among authors: lu zl. Neuroendocrinology. 2006;84(5):301-8. doi: 10.1159/000098147. Epub 2006 Dec 19. Neuroendocrinology. 2006. PMID: 17179725

2

Identification of a novel ligand binding residue Arg38(1.35) in the human gonadotropin-releasing hormone receptor.

Stewart AJ, Sellar R, Wilson DJ, Millar RP, Lu ZL. Stewart AJ, et al. Among authors: lu zl. Mol Pharmacol. 2008 Jan;73(1):75-81. doi: 10.1124/mol.107.040816. Epub 2007 Oct 17. Mol Pharmacol. 2008. PMID: 17942747

3

Antiproliferative effects of GnRH agonists: prospects and problems for cancer therapy.

White CD, Stewart AJ, Lu ZL, Millar RP, Morgan K. White CD, et al. Among authors: lu zl. Neuroendocrinology. 2008;88(2):67-79. doi: 10.1159/000119093. Epub 2008 Feb 29. Neuroendocrinology. 2008. PMID: 18309229 Review.

4

Gonadotropin-releasing hormone receptors.

Millar RP, Lu ZL, Pawson AJ, Flanagan CA, Morgan K, Maudsley SR. Millar RP, et al. Among authors: lu zl. Endocr Rev. 2004 Apr;25(2):235-75. doi: 10.1210/er.2003-0002. Endocr Rev. 2004. PMID: 15082521 Review.

5

Bovine and ovine gonadotropin-releasing hormone (GnRH)-II ligand precursors and type II GnRH receptor genes are functionally inactivated.

Morgan K, Sellar R, Pawson AJ, Lu ZL, Millar RP. Morgan K, et al. Among authors: lu zl. Endocrinology. 2006 Nov;147(11):5041-51. doi: 10.1210/en.2006-0222. Epub 2006 Aug 17. Endocrinology. 2006. PMID: 16916952

6

Conserved amino acid residues that are important for ligand binding in the type I gonadotropin-releasing hormone (GnRH) receptor are required for high potency of GnRH II at the type II GnRH receptor.

Mamputha S, Lu ZL, Roeske RW, Millar RP, Katz AA, Flanagan CA. Mamputha S, et al. Among authors: lu zl. Mol Endocrinol. 2007 Jan;21(1):281-92. doi: 10.1210/me.2006-0150. Epub 2006 Sep 14. Mol Endocrinol. 2007. PMID: 16973761

7

Diversity of actions of GnRHs mediated by ligand-induced selective signaling.

Millar RP, Pawson AJ, Morgan K, Rissman EF, Lu ZL. Millar RP, et al. Among authors: lu zl. Front Neuroendocrinol. 2008 Jan;29(1):17-35. doi: 10.1016/j.yfrne.2007.06.002. Epub 2007 Aug 23. Front Neuroendocrinol. 2008. PMID: 17976709 Free PMC article. Review.

8

Identification of Tyr(290(6.58)) of the human gonadotropin-releasing hormone (GnRH) receptor as a contact residue for both GnRH I and GnRH II: importance for high-affinity binding and receptor activation.

Coetsee M, Millar RP, Flanagan CA, Lu ZL. Coetsee M, et al. Among authors: lu zl. Biochemistry. 2008 Sep 30;47(39):10305-13. doi: 10.1021/bi800911z. Epub 2008 Sep 5. Biochemistry. 2008. PMID: 18771291

9

Mutations remote from the human gonadotropin-releasing hormone (GnRH) receptor-binding sites specifically increase binding affinity for GnRH II but not GnRH I: evidence for ligand-selective, receptor-active conformations.

Lu ZL, Gallagher R, Sellar R, Coetsee M, Millar RP. Lu ZL, et al. J Biol Chem. 2005 Aug 19;280(33):29796-803. doi: 10.1074/jbc.M413520200. Epub 2005 Jun 20. J Biol Chem. 2005. PMID: 15967801 Free article.

10

Mammalian type I gonadotropin-releasing hormone receptors undergo slow, constitutive, agonist-independent internalization.

Pawson AJ, Faccenda E, Maudsley S, Lu ZL, Naor Z, Millar RP. Pawson AJ, et al. Among authors: lu zl. Endocrinology. 2008 Mar;149(3):1415-22. doi: 10.1210/en.2007-1159. Epub 2007 Nov 26. Endocrinology. 2008. PMID: 18039780

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