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Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients.
Wang TL, Diaz LA Jr, Romans K, Bardelli A, Saha S, Galizia G, Choti M, Donehower R, Parmigiani G, Shih IeM, Iacobuzio-Donahue C, Kinzler KW, Vogelstein B, Lengauer C, Velculescu VE. Wang TL, et al. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):3089-94. doi: 10.1073/pnas.0308716101. Epub 2004 Feb 17. Proc Natl Acad Sci U S A. 2004. PMID: 14970324 Free PMC article.
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses.
Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Kamiyama H, Jimeno A, Hong SM, Fu B, Lin MT, Calhoun ES, Kamiyama M, Walter K, Nikolskaya T, Nikolsky Y, Hartigan J, Smith DR, Hidalgo M, Leach SD, Klein AP, Jaffee EM, Goggins M, Maitra A, Iacobuzio-Donahue C, Eshleman JR, Kern SE, Hruban RH, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu VE, Kinzler KW. Jones S, et al. Science. 2008 Sep 26;321(5897):1801-6. doi: 10.1126/science.1164368. Epub 2008 Sep 4. Science. 2008. PMID: 18772397 Free PMC article.
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene.
Jones S, Hruban RH, Kamiyama M, Borges M, Zhang X, Parsons DW, Lin JC, Palmisano E, Brune K, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Parmigiani G, Kern SE, Velculescu VE, Kinzler KW, Vogelstein B, Eshleman JR, Goggins M, Klein AP. Jones S, et al. Science. 2009 Apr 10;324(5924):217. doi: 10.1126/science.1171202. Epub 2009 Mar 5. Science. 2009. PMID: 19264984 Free PMC article.
Genetic mutations associated with cigarette smoking in pancreatic cancer.
Blackford A, Parmigiani G, Kensler TW, Wolfgang C, Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Klein A, Cameron JL, Olino K, Schulick R, Winter J, Vogelstein B, Velculescu VE, Kinzler KW, Hruban RH. Blackford A, et al. Cancer Res. 2009 Apr 15;69(8):3681-8. doi: 10.1158/0008-5472.CAN-09-0015. Epub 2009 Apr 7. Cancer Res. 2009. PMID: 19351817 Free PMC article.
SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer.
Blackford A, Serrano OK, Wolfgang CL, Parmigiani G, Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Cameron JL, Olino K, Schulick R, Winter J, Herman JM, Laheru D, Klein AP, Vogelstein B, Kinzler KW, Velculescu VE, Hruban RH. Blackford A, et al. Clin Cancer Res. 2009 Jul 15;15(14):4674-9. doi: 10.1158/1078-0432.CCR-09-0227. Epub 2009 Jul 7. Clin Cancer Res. 2009. PMID: 19584151 Free PMC article.
Cross-platform Comparison of Two Pancreatic Cancer Phenotypes.
Scharpf RB, Iacobuzio-Donahue CA, Cope L, Ruczinski I, Garrett-Mayer E, Lakkur S, Campagna D, Parmigiani G. Scharpf RB, et al. Cancer Inform. 2010 Nov 1;9:257-64. doi: 10.4137/CIN.S5755. Cancer Inform. 2010. PMID: 21082040 Free PMC article.
Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays.
Iacobuzio-Donahue CA, Maitra A, Olsen M, Lowe AW, van Heek NT, Rosty C, Walter K, Sato N, Parker A, Ashfaq R, Jaffee E, Ryu B, Jones J, Eshleman JR, Yeo CJ, Cameron JL, Kern SE, Hruban RH, Brown PO, Goggins M. Iacobuzio-Donahue CA, et al. Am J Pathol. 2003 Apr;162(4):1151-62. doi: 10.1016/S0002-9440(10)63911-9. Am J Pathol. 2003. PMID: 12651607 Free PMC article.
353 results