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The antiapoptotic protein BAG3 is expressed in thyroid carcinomas and modulates apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand.
Chiappetta G, Ammirante M, Basile A, Rosati A, Festa M, Monaco M, Vuttariello E, Pasquinelli R, Arra C, Zerilli M, Todaro M, Stassi G, Pezzullo L, Gentilella A, Tosco A, Pascale M, Marzullo L, Belisario MA, Turco MC, Leone A. Chiappetta G, et al. Among authors: pasquinelli r. J Clin Endocrinol Metab. 2007 Mar;92(3):1159-63. doi: 10.1210/jc.2006-1712. Epub 2006 Dec 12. J Clin Endocrinol Metab. 2007. PMID: 17164298
BAG3 down-modulation reduces anaplastic thyroid tumor growth by enhancing proteasome-mediated degradation of BRAF protein.
Chiappetta G, Basile A, Arra C, Califano D, Pasquinelli R, Barbieri A, De Simone V, Rea D, Giudice A, Pezzullo L, De Laurenzi V, Botti G, Losito S, Conforti D, Turco MC. Chiappetta G, et al. Among authors: pasquinelli r. J Clin Endocrinol Metab. 2012 Jan;97(1):E115-20. doi: 10.1210/jc.2011-0484. Epub 2011 Nov 9. J Clin Endocrinol Metab. 2012. PMID: 22072743
The anti-apoptotic BAG3 protein is expressed in lung carcinomas and regulates small cell lung carcinoma (SCLC) tumor growth.
Chiappetta G, Basile A, Barbieri A, Falco A, Rosati A, Festa M, Pasquinelli R, Califano D, Palma G, Costanzo R, Barcaroli D, Capunzo M, Franco R, Rocco G, Pascale M, Turco MC, De Laurenzi V, Arra C. Chiappetta G, et al. Among authors: pasquinelli r. Oncotarget. 2014 Aug 30;5(16):6846-53. doi: 10.18632/oncotarget.2261. Oncotarget. 2014. PMID: 25149536 Free PMC article.
Overexpression of the S-phase kinase-associated protein 2 in thyroid cancer.
Chiappetta G, De Marco C, Quintiero A, Califano D, Gherardi S, Malanga D, Scrima M, Montero-Conde C, Cito L, Monaco M, Motti ML, Pasquinelli R, Agosti V, Robledo M, Fusco A, Viglietto G. Chiappetta G, et al. Among authors: pasquinelli r. Endocr Relat Cancer. 2007 Jun;14(2):405-20. doi: 10.1677/ERC-06-0030. Endocr Relat Cancer. 2007. PMID: 17639054
PATZ1 acts as a tumor suppressor in thyroid cancer via targeting p53-dependent genes involved in EMT and cell migration.
Chiappetta G, Valentino T, Vitiello M, Pasquinelli R, Monaco M, Palma G, Sepe R, Luciano A, Pallante P, Palmieri D, Aiello C, Rea D, Losito SN, Arra C, Fusco A, Fedele M. Chiappetta G, et al. Among authors: pasquinelli r. Oncotarget. 2015 Mar 10;6(7):5310-23. doi: 10.18632/oncotarget.2776. Oncotarget. 2015. PMID: 25595894 Free PMC article.
27 results