Adnane J - Search Results

1

Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models.

Chang YS, Adnane J, Trail PA, Levy J, Henderson A, Xue D, Bortolon E, Ichetovkin M, Chen C, McNabola A, Wilkie D, Carter CA, Taylor IC, Lynch M, Wilhelm S. Chang YS, et al. Among authors: adnane j. Cancer Chemother Pharmacol. 2007 Apr;59(5):561-74. doi: 10.1007/s00280-006-0393-4. Epub 2006 Dec 8. Cancer Chemother Pharmacol. 2007. PMID: 17160391

2

Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter.

Delarue FL, Adnane J, Joshi B, Blaskovich MA, Wang DA, Hawker J, Bizouarn F, Ohkanda J, Zhu K, Hamilton AD, Chellappan S, Sebti SM. Delarue FL, et al. Among authors: adnane j. Oncogene. 2007 Feb 1;26(5):633-40. doi: 10.1038/sj.onc.1209819. Epub 2006 Aug 14. Oncogene. 2007. PMID: 16909123

3

Loss of the cell cycle inhibitors p21(Cip1) and p27(Kip1) enhances tumorigenesis in knockout mouse models.

Jackson RJ, Adnane J, Coppola D, Cantor A, Sebti SM, Pledger WJ. Jackson RJ, et al. Among authors: adnane j. Oncogene. 2002 Dec 5;21(55):8486-97. doi: 10.1038/sj.onc.1205946. Oncogene. 2002. PMID: 12466968

4

Suppression of rho B expression in invasive carcinoma from head and neck cancer patients.

Adnane J, Muro-Cacho C, Mathews L, Sebti SM, Muñoz-Antonia T. Adnane J, et al. Clin Cancer Res. 2002 Jul;8(7):2225-32. Clin Cancer Res. 2002. PMID: 12114424

5

RhoB, not RhoA, represses the transcription of the transforming growth factor beta type II receptor by a mechanism involving activator protein 1.

Adnane J, Seijo E, Chen Z, Bizouarn F, Leal M, Sebti SM, Muñoz-Antonia T. Adnane J, et al. J Biol Chem. 2002 Mar 8;277(10):8500-7. doi: 10.1074/jbc.M104367200. Epub 2001 Dec 11. J Biol Chem. 2002. PMID: 11741970 Free article.

6

Inhibition of farnesyltransferase increases TGFbeta type II receptor expression and enhances the responsiveness of human cancer cells to TGFbeta.

Adnane J, Bizouarn FA, Chen Z, Ohkanda J, Hamilton AD, Munoz-Antonia T, Sebti SM. Adnane J, et al. Oncogene. 2000 Nov 16;19(48):5525-33. doi: 10.1038/sj.onc.1203920. Oncogene. 2000. PMID: 11114730

7

Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model.

Adnane J, Jackson RJ, Nicosia SV, Cantor AB, Pledger WJ, Sebti SM. Adnane J, et al. Oncogene. 2000 Nov 9;19(47):5338-47. doi: 10.1038/sj.onc.1203956. Oncogene. 2000. PMID: 11103935

8

Cocaine activates platelets and increases the formation of circulating platelet containing microaggregates in humans.

Heesch CM, Wilhelm CR, Ristich J, Adnane J, Bontempo FA, Wagner WR. Heesch CM, et al. Among authors: adnane j. Heart. 2000 Jun;83(6):688-95. doi: 10.1136/heart.83.6.688. Heart. 2000. PMID: 10814631 Free PMC article. Clinical Trial.

9

Both farnesylated and geranylgeranylated RhoB inhibit malignant transformation and suppress human tumor growth in nude mice.

Chen Z, Sun J, Pradines A, Favre G, Adnane J, Sebti SM. Chen Z, et al. Among authors: adnane j. J Biol Chem. 2000 Jun 16;275(24):17974-8. doi: 10.1074/jbc.C000145200. J Biol Chem. 2000. PMID: 10770919 Free article.

10

Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein.

Turkson J, Bowman T, Adnane J, Zhang Y, Djeu JY, Sekharam M, Frank DA, Holzman LB, Wu J, Sebti S, Jove R. Turkson J, et al. Among authors: adnane j. Mol Cell Biol. 1999 Nov;19(11):7519-28. doi: 10.1128/MCB.19.11.7519. Mol Cell Biol. 1999. PMID: 10523640 Free PMC article.

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