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Mitochondrial dysfunction induced by a cytotoxic adenine dinucleotide produced by ADP-ribosyl cyclases from cADPR.
Bruzzone S, Dodoni G, Kaludercic N, Basile G, Millo E, De Flora A, Di Lisa F, Zocchi E. Bruzzone S, et al. J Biol Chem. 2007 Feb 16;282(7):5045-5052. doi: 10.1074/jbc.M609802200. Epub 2006 Dec 8. J Biol Chem. 2007. PMID: 17158448 Free article.
ADP-ribosyl cyclases were previously shown to produce three new adenine dinucleotides, P1,P2 diadenosine 5'-diphosphate (Ap2A) and two isomers thereof (P18 and P24), from cyclic ADP-ribose (cADPR) and adenine (Basile, G., Taglialatela-Scafati, O., Damonte, G., Armirotti, A., B …
ADP-ribosyl cyclases were previously shown to produce three new adenine dinucleotides, P1,P2 diadenosine 5'-diphosphate (Ap2A) and two isome …
Dimeric and tetrameric forms of catalytically active transmembrane CD38 in transfected HeLa cells.
Bruzzone S, Guida L, Franco L, Zocchi E, Corte G, De Flora A. Bruzzone S, et al. FEBS Lett. 1998 Aug 21;433(3):275-8. doi: 10.1016/s0014-5793(98)00929-6. FEBS Lett. 1998. PMID: 9744810 Free article.
CD38, a type II transmembrane glycoprotein, behaves as a catalytically active transporter responsible for ectocellular generation of cyclic ADP-ribose (cADPR) from NAD+ and for subsequent influx of cADPR across membranes [Franco, L., Guida, L., Bruzzone, S., Zocchi, …
CD38, a type II transmembrane glycoprotein, behaves as a catalytically active transporter responsible for ectocellular generation of cyclic …
Topology of CD38.
De Flora A, Franco L, Guida L, Bruzzone S, Usai C, Zocchi E. De Flora A, et al. Among authors: bruzzone s. Chem Immunol. 2000;75:79-98. doi: 10.1159/000058764. Chem Immunol. 2000. PMID: 10851780 Review. No abstract available.
206 results