Van de Casteele M - Search Results

1

Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation.

Cai Y, Martens GA, Hinke SA, Heimberg H, Pipeleers D, Van de Casteele M. Cai Y, et al. Among authors: van de casteele m. Free Radic Biol Med. 2007 Jan 1;42(1):64-78. doi: 10.1016/j.freeradbiomed.2006.09.018. Epub 2006 Sep 27. Free Radic Biol Med. 2007. PMID: 17157194

2

Metformin-induced stimulation of AMP-activated protein kinase in beta-cells impairs their glucose responsiveness and can lead to apoptosis.

Kefas BA, Cai Y, Kerckhofs K, Ling Z, Martens G, Heimberg H, Pipeleers D, Van de Casteele M. Kefas BA, et al. Among authors: van de casteele m. Biochem Pharmacol. 2004 Aug 1;68(3):409-16. doi: 10.1016/j.bcp.2004.04.003. Biochem Pharmacol. 2004. PMID: 15242807

3

Glucose suppresses superoxide generation in metabolically responsive pancreatic beta cells.

Martens GA, Cai Y, Hinke S, Stangé G, Van de Casteele M, Pipeleers D. Martens GA, et al. Among authors: van de casteele m. J Biol Chem. 2005 May 27;280(21):20389-96. doi: 10.1074/jbc.M411869200. Epub 2005 Mar 17. J Biol Chem. 2005. PMID: 15774474 Free article.

4

Adiponectin-mediated stimulation of AMP-activated protein kinase (AMPK) in pancreatic beta cells.

Huypens P, Moens K, Heimberg H, Ling Z, Pipeleers D, Van de Casteele M. Huypens P, et al. Among authors: van de casteele m. Life Sci. 2005 Jul 29;77(11):1273-82. doi: 10.1016/j.lfs.2005.03.008. Life Sci. 2005. PMID: 15893773

5

Metformin reduces adiponectin protein expression and release in 3T3-L1 adipocytes involving activation of AMP activated protein kinase.

Huypens P, Quartier E, Pipeleers D, Van de Casteele M. Huypens P, et al. Among authors: van de casteele m. Eur J Pharmacol. 2005 Aug 22;518(2-3):90-5. doi: 10.1016/j.ejphar.2005.06.016. Eur J Pharmacol. 2005. PMID: 16039647

6

Glycemic control of apoptosis in the pancreatic beta cell: danger of extremes?

Martens GA, Van de Casteele M. Martens GA, et al. Among authors: van de casteele m. Antioxid Redox Signal. 2007 Mar;9(3):309-17. doi: 10.1089/ars.2006.1466. Antioxid Redox Signal. 2007. PMID: 17184175 Review.

7

Akt activation protects pancreatic beta cells from AMPK-mediated death through stimulation of mTOR.

Cai Y, Wang Q, Ling Z, Pipeleers D, McDermott P, Pende M, Heimberg H, Van de Casteele M. Cai Y, et al. Among authors: van de casteele m. Biochem Pharmacol. 2008 May 15;75(10):1981-93. doi: 10.1016/j.bcp.2008.02.019. Epub 2008 Feb 26. Biochem Pharmacol. 2008. PMID: 18377870

8

Prolonged culture in low glucose induces apoptosis of rat pancreatic beta-cells through induction of c-myc.

Van de Casteele M, Kefas BA, Cai Y, Heimberg H, Scott DK, Henquin JC, Pipeleers D, Jonas JC. Van de Casteele M, et al. Biochem Biophys Res Commun. 2003 Dec 26;312(4):937-44. doi: 10.1016/j.bbrc.2003.11.013. Biochem Biophys Res Commun. 2003. PMID: 14651961

9

Interaction of glibenclamide and metformin at the level of translation in pancreatic β cells.

Wang Q, Cai Y, Van de Casteele M, Pipeleers D, Ling Z. Wang Q, et al. Among authors: van de casteele m. J Endocrinol. 2011 Feb;208(2):161-9. doi: 10.1677/JOE-10-0372. Epub 2010 Nov 17. J Endocrinol. 2011. PMID: 21084384

10

Specific expression of Bax-omega in pancreatic beta-cells is down-regulated by cytokines before the onset of apoptosis.

Van de Casteele M, Kefas BA, Ling Z, Heimberg H, Pipeleers DG. Van de Casteele M, et al. Endocrinology. 2002 Jan;143(1):320-6. doi: 10.1210/endo.143.1.8574. Endocrinology. 2002. PMID: 11751624

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