Morita K - Search Results

1

SNP genotyping by allele-specific PCR using ENA primers.

Koizumi M, Morita K, Takagi M, Yasumo H, Kasuya A. Koizumi M, et al. Among authors: morita k. Nucleic Acids Symp Ser (Oxf). 2005;(49):47-8. doi: 10.1093/nass/49.1.47. Nucleic Acids Symp Ser (Oxf). 2005. PMID: 17150626

2

2'-O,4'-C-ethylene-bridged nucleic acids (ENA): highly nuclease-resistant and thermodynamically stable oligonucleotides for antisense drug.

Morita K, Hasegawa C, Kaneko M, Tsutsumi S, Sone J, Ishikawa T, Imanishi T, Koizumi M. Morita K, et al. Bioorg Med Chem Lett. 2002 Jan 7;12(1):73-6. doi: 10.1016/s0960-894x(01)00683-7. Bioorg Med Chem Lett. 2002. PMID: 11738576

3

3'-amino-2',4'-BNA: novel bridged nucleic acids having an N3'-->P5' phosphoramidate linkage.

Obika S, Onoda M, Morita K, Andoh J, Koizumi M, Imanishi T. Obika S, et al. Among authors: morita k. Chem Commun (Camb). 2001 Oct 7;(19):1992-3. doi: 10.1039/b105640a. Chem Commun (Camb). 2001. PMID: 12240255

4

Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3'-ends of siRNAs.

Hamada M, Ohtsuka T, Kawaida R, Koizumi M, Morita K, Furukawa H, Imanishi T, Miyagishi M, Taira K. Hamada M, et al. Among authors: morita k. Antisense Nucleic Acid Drug Dev. 2002 Oct;12(5):301-9. doi: 10.1089/108729002761381285. Antisense Nucleic Acid Drug Dev. 2002. PMID: 12477280

5

Synthesis and properties of 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) as effective antisense oligonucleotides.

Morita K, Takagi M, Hasegawa C, Kaneko M, Tsutsumi S, Sone J, Ishikawa T, Imanishi T, Koizumi M. Morita K, et al. Bioorg Med Chem. 2003 May 15;11(10):2211-26. doi: 10.1016/s0968-0896(03)00115-9. Bioorg Med Chem. 2003. PMID: 12713831

6

Triplex formation with 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) having C3'-endo conformation at physiological pH.

Koizumi M, Morita K, Daigo M, Tsutsumi S, Abe K, Obika S, Imanishi T. Koizumi M, et al. Among authors: morita k. Nucleic Acids Res. 2003 Jun 15;31(12):3267-73. doi: 10.1093/nar/gkg416. Nucleic Acids Res. 2003. PMID: 12799454 Free PMC article.

7

2'-O,4'-C-ethylene-bridged nucleic acids (ENA) with nuclease-resistance and high affinity for RNA.

Morita K, Hasegawa C, Kaneko M, Tsutsumi S, Sone J, Ishikawa T, Imanishi T, Koizumi M. Morita K, et al. Nucleic Acids Res Suppl. 2001;(1):241-2. doi: 10.1093/nass/1.1.241. Nucleic Acids Res Suppl. 2001. PMID: 12836354

8

Down-regulation of VEGF mRNA expression by 2'-O,4'-C-ethylene-bridged nucleic acid (ENA) antisense oligonucleotides and investigation of non-target gene expression.

Morita K, Yamate K, Kurakata S, Abe K, Imanishi T, Koizumi M. Morita K, et al. Nucleic Acids Res Suppl. 2002;(2):99-100. doi: 10.1093/nass/2.1.99. Nucleic Acids Res Suppl. 2002. PMID: 12903124

9

Design and synthesis of oatp subtype-specific antisense oligonucleotides having 2'-O,4'-C-ethylene-bridged nucleic acids (ENA).

Takagi M, Morita K, Nakai D, Nakagomi R, Tokui T, Koizumi M. Takagi M, et al. Among authors: morita k. Nucleic Acids Res Suppl. 2003;(3):83-4. doi: 10.1093/nass/3.1.83. Nucleic Acids Res Suppl. 2003. PMID: 14510391

10

2'-O,4'-C-ethylene-bridged nucleic acid (ENA) for effective antisense formation.

Morita K, Yamate K, Kurakata S, Watanabe K, Imanishi T, Koizumi M. Morita K, et al. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1619-21. doi: 10.1081/NCN-120023082. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565480

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