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Synergistic antitumor activity of ZD6474, an inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling, with gemcitabine and ionizing radiation against pancreatic cancer.
Bianco C, Giovannetti E, Ciardiello F, Mey V, Nannizzi S, Tortora G, Troiani T, Pasqualetti F, Eckhardt G, de Liguoro M, Ricciardi S, Del Tacca M, Raben D, Cionini L, Danesi R. Bianco C, et al. Among authors: cionini l. Clin Cancer Res. 2006 Dec 1;12(23):7099-107. doi: 10.1158/1078-0432.CCR-06-0833. Clin Cancer Res. 2006. PMID: 17145834
Antitumor activity of ZD6126, a novel vascular-targeting agent, is enhanced when combined with ZD1839, an epidermal growth factor receptor tyrosine kinase inhibitor, and potentiates the effects of radiation in a human non-small cell lung cancer xenograft model.
Raben D, Bianco C, Damiano V, Bianco R, Melisi D, Mignogna C, D'Armiento FP, Cionini L, Bianco AR, Tortora G, Ciardiello F, Bunn P. Raben D, et al. Among authors: cionini l. Mol Cancer Ther. 2004 Aug;3(8):977-83. Mol Cancer Ther. 2004. PMID: 15299080
96 results