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Page 1
Strategy for genotoxicity testing: hazard identification and risk assessment in relation to in vitro testing.
Thybaud V, Aardema M, Clements J, Dearfield K, Galloway S, Hayashi M, Jacobson-Kram D, Kirkland D, MacGregor JT, Marzin D, Ohyama W, Schuler M, Suzuki H, Zeiger E; Expert Working Group on Hazard Identification and Risk Assessment in Relation to In Vitro Testing. Thybaud V, et al. Among authors: aardema m. Mutat Res. 2007 Feb 3;627(1):41-58. doi: 10.1016/j.mrgentox.2006.10.003. Epub 2006 Nov 27. Mutat Res. 2007. PMID: 17126066
Workshop summary: Top concentration for in vitro mammalian cell genotoxicity assays; and report from working group on toxicity measures and top concentration for in vitro cytogenetics assays (chromosome aberrations and micronucleus).
Galloway S, Lorge E, Aardema MJ, Eastmond D, Fellows M, Heflich R, Kirkland D, Levy DD, Lynch AM, Marzin D, Morita T, Schuler M, Speit G. Galloway S, et al. Among authors: aardema mj. Mutat Res. 2011 Aug 16;723(2):77-83. doi: 10.1016/j.mrgentox.2011.01.003. Epub 2011 Jan 19. Mutat Res. 2011. PMID: 21255675
Standardized cell sources and recommendations for good cell culture practices in genotoxicity testing.
Lorge E, Moore MM, Clements J, O'Donovan M, Fellows MD, Honma M, Kohara A, Galloway S, Armstrong MJ, Thybaud V, Gollapudi B, Aardema MJ, Tanir JY. Lorge E, et al. Among authors: aardema mj. Mutat Res Genet Toxicol Environ Mutagen. 2016 Oct;809:1-15. doi: 10.1016/j.mrgentox.2016.08.001. Epub 2016 Aug 3. Mutat Res Genet Toxicol Environ Mutagen. 2016. PMID: 27692294 Free article.
How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.
Kirkland D, Pfuhler S, Tweats D, Aardema M, Corvi R, Darroudi F, Elhajouji A, Glatt H, Hastwell P, Hayashi M, Kasper P, Kirchner S, Lynch A, Marzin D, Maurici D, Meunier JR, Müller L, Nohynek G, Parry J, Parry E, Thybaud V, Tice R, van Benthem J, Vanparys P, White P. Kirkland D, et al. Among authors: aardema m. Mutat Res. 2007 Mar 30;628(1):31-55. doi: 10.1016/j.mrgentox.2006.11.008. Epub 2007 Jan 13. Mutat Res. 2007. PMID: 17293159
Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens II. Further analysis of mammalian cell results, relative predictivity and tumour profiles.
Kirkland D, Aardema M, Müller L, Makoto H. Kirkland D, et al. Among authors: aardema m. Mutat Res. 2006 Sep 19;608(1):29-42. doi: 10.1016/j.mrgentox.2006.04.017. Mutat Res. 2006. PMID: 16769241
One of the consequences of the low specificity of the in vitro mammalian cell genotoxicity assays reported in our previous paper [D. Kirkland, M. Aardema, L. Henderson, L. Muller, Evaluation of the ability of a battery of three in vitro genotoxicity tests to discrim …
One of the consequences of the low specificity of the in vitro mammalian cell genotoxicity assays reported in our previous paper [D. Kirklan …
Improvement of in vivo genotoxicity assessment: combination of acute tests and integration into standard toxicity testing.
Rothfuss A, Honma M, Czich A, Aardema MJ, Burlinson B, Galloway S, Hamada S, Kirkland D, Heflich RH, Howe J, Nakajima M, O'Donovan M, Plappert-Helbig U, Priestley C, Recio L, Schuler M, Uno Y, Martus HJ. Rothfuss A, et al. Among authors: aardema mj. Mutat Res. 2011 Aug 16;723(2):108-20. doi: 10.1016/j.mrgentox.2010.12.005. Epub 2010 Dec 21. Mutat Res. 2011. PMID: 21182982
148 results