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Mice with targeted disruption of spermidine/spermine N1-acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging.
Niiranen K, Keinänen TA, Pirinen E, Heikkinen S, Tusa M, Fatrai S, Suppola S, Pietilä M, Uimari A, Laakso M, Alhonen L, Jänne J. Niiranen K, et al. Among authors: keinanen ta. J Cell Mol Med. 2006 Oct-Dec;10(4):933-45. doi: 10.1111/j.1582-4934.2006.tb00536.x. J Cell Mol Med. 2006. PMID: 17125596 Free article.
Targeted disruption of spermidine/spermine N1-acetyltransferase gene in mouse embryonic stem cells. Effects on polyamine homeostasis and sensitivity to polyamine analogues.
Niiranen K, Pietilä M, Pirttilä TJ, Järvinen A, Halmekytö M, Korhonen VP, Keinänen TA, Alhonen L, Jänne J. Niiranen K, et al. Among authors: keinanen ta. J Biol Chem. 2002 Jul 12;277(28):25323-8. doi: 10.1074/jbc.M203599200. Epub 2002 May 8. J Biol Chem. 2002. PMID: 12000764 Free article.
Animal disease models generated by genetic engineering of polyamine metabolism.
Jänne J, Alhonen L, Keinänen TA, Pietilä M, Uimari A, Pirinen E, Hyvönen MT, Järvinen A. Jänne J, et al. Among authors: keinanen ta. J Cell Mol Med. 2005 Oct-Dec;9(4):865-82. doi: 10.1111/j.1582-4934.2005.tb00385.x. J Cell Mol Med. 2005. PMID: 16364196 Free PMC article. Review.
Genetic manipulation of polyamine catabolism in rodents.
Jänne J, Alhonen L, Pietilä M, Keinänen TA, Uimari A, Hyvönen MT, Pirinen E, Järvinen A. Jänne J, et al. Among authors: keinanen ta. J Biochem. 2006 Feb;139(2):155-60. doi: 10.1093/jb/mvj035. J Biochem. 2006. PMID: 16452302 Review.
Spermidine is indispensable in differentiation of 3T3-L1 fibroblasts to adipocytes.
Vuohelainen S, Pirinen E, Cerrada-Gimenez M, Keinänen TA, Uimari A, Pietilä M, Khomutov AR, Jänne J, Alhonen L. Vuohelainen S, et al. Among authors: keinanen ta. J Cell Mol Med. 2010 Jun;14(6B):1683-92. doi: 10.1111/j.1582-4934.2009.00808.x. Epub 2009 Jun 16. J Cell Mol Med. 2010. PMID: 19538475 Free PMC article.
80 results