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An efficient rapid system for profiling the cellular activities of molecular libraries.
Melnick JS, Janes J, Kim S, Chang JY, Sipes DG, Gunderson D, Jarnes L, Matzen JT, Garcia ME, Hood TL, Beigi R, Xia G, Harig RA, Asatryan H, Yan SF, Zhou Y, Gu XJ, Saadat A, Zhou V, King FJ, Shaw CM, Su AI, Downs R, Gray NS, Schultz PG, Warmuth M, Caldwell JS. Melnick JS, et al. Among authors: caldwell js. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3153-8. doi: 10.1073/pnas.0511292103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492761 Free PMC article.
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
Plouffe D, Brinker A, McNamara C, Henson K, Kato N, Kuhen K, Nagle A, Adrián F, Matzen JT, Anderson P, Nam TG, Gray NS, Chatterjee A, Janes J, Yan SF, Trager R, Caldwell JS, Schultz PG, Zhou Y, Winzeler EA. Plouffe D, et al. Among authors: caldwell js. Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9059-64. doi: 10.1073/pnas.0802982105. Epub 2008 Jun 25. Proc Natl Acad Sci U S A. 2008. PMID: 18579783 Free PMC article.
Genome-scale functional profiling of the mammalian AP-1 signaling pathway.
Chanda SK, White S, Orth AP, Reisdorph R, Miraglia L, Thomas RS, DeJesus P, Mason DE, Huang Q, Vega R, Yu DH, Nelson CG, Smith BM, Terry R, Linford AS, Yu Y, Chirn GW, Song C, Labow MA, Cohen D, King FJ, Peters EC, Schultz PG, Vogt PK, Hogenesch JB, Caldwell JS. Chanda SK, et al. Among authors: caldwell js. Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12153-8. doi: 10.1073/pnas.1934839100. Epub 2003 Sep 26. Proc Natl Acad Sci U S A. 2003. PMID: 14514886 Free PMC article.
4-Aminopyrimidines as novel HIV-1 inhibitors.
Gadhachanda VR, Wu B, Wang Z, Kuhen KL, Caldwell J, Zondler H, Walter H, Havenhand M, He Y. Gadhachanda VR, et al. Bioorg Med Chem Lett. 2007 Jan 1;17(1):260-5. doi: 10.1016/j.bmcl.2006.09.047. Epub 2006 Oct 10. Bioorg Med Chem Lett. 2007. PMID: 17035019
60 results