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Migration from a mitogenic niche promotes cell-cycle exit.
Choi Y, Borghesani PR, Chan JA, Segal RA. Choi Y, et al. Among authors: segal ra. J Neurosci. 2005 Nov 9;25(45):10437-45. doi: 10.1523/JNEUROSCI.1559-05.2005. J Neurosci. 2005. PMID: 16280582 Free PMC article.
Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses.
Chan JA, Balasubramanian S, Witt RM, Nazemi KJ, Choi Y, Pazyra-Murphy MF, Walsh CO, Thompson M, Segal RA. Chan JA, et al. Among authors: segal ra. Nat Neurosci. 2009 Apr;12(4):409-17. doi: 10.1038/nn.2287. Epub 2009 Mar 15. Nat Neurosci. 2009. PMID: 19287388 Free PMC article.
Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation.
Witt RM, Hecht ML, Pazyra-Murphy MF, Cohen SM, Noti C, van Kuppevelt TH, Fuller M, Chan JA, Hopwood JJ, Seeberger PH, Segal RA. Witt RM, et al. Among authors: segal ra. J Biol Chem. 2013 Sep 6;288(36):26275-26288. doi: 10.1074/jbc.M112.438937. Epub 2013 Jul 18. J Biol Chem. 2013. PMID: 23867465 Free PMC article.
Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities.
Filbin MG, Dabral SK, Pazyra-Murphy MF, Ramkissoon S, Kung AL, Pak E, Chung J, Theisen MA, Sun Y, Franchetti Y, Sun Y, Shulman DS, Redjal N, Tabak B, Beroukhim R, Wang Q, Zhao J, Dorsch M, Buonamici S, Ligon KL, Kelleher JF, Segal RA. Filbin MG, et al. Among authors: segal ra. Nat Med. 2013 Nov;19(11):1518-23. doi: 10.1038/nm.3328. Epub 2013 Sep 29. Nat Med. 2013. PMID: 24076665 Free PMC article.
Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype.
Bergthold G, Bandopadhayay P, Hoshida Y, Ramkissoon S, Ramkissoon L, Rich B, Maire CL, Paolella BR, Schumacher SE, Tabak B, Ferrer-Luna R, Ozek M, Sav A, Santagata S, Wen PY, Goumnerova LC, Ligon AH, Stiles C, Segal R, Golub T, Grill J, Ligon KL, Chan JA, Kieran MW, Beroukhim R. Bergthold G, et al. Neuro Oncol. 2015 Nov;17(11):1486-96. doi: 10.1093/neuonc/nov045. Epub 2015 Mar 29. Neuro Oncol. 2015. PMID: 25825052 Free PMC article.
136 results