Walsh CT - Search Results

1

Enzymatic generation of the antimetabolite gamma,gamma-dichloroaminobutyrate by NRPS and mononuclear iron halogenase action in a streptomycete.

Ueki M, Galonić DP, Vaillancourt FH, Garneau-Tsodikova S, Yeh E, Vosburg DA, Schroeder FC, Osada H, Walsh CT. Ueki M, et al. Among authors: walsh ct. Chem Biol. 2006 Nov;13(11):1183-91. doi: 10.1016/j.chembiol.2006.09.012. Chem Biol. 2006. PMID: 17114000

2

Generation of D amino acid residues in assembly of arthrofactin by dual condensation/epimerization domains.

Balibar CJ, Vaillancourt FH, Walsh CT. Balibar CJ, et al. Among authors: walsh ct. Chem Biol. 2005 Nov;12(11):1189-200. doi: 10.1016/j.chembiol.2005.08.010. Chem Biol. 2005. PMID: 16298298

3

Characterization of SyrC, an aminoacyltransferase shuttling threonyl and chlorothreonyl residues in the syringomycin biosynthetic assembly line.

Singh GM, Vaillancourt FH, Yin J, Walsh CT. Singh GM, et al. Among authors: walsh ct. Chem Biol. 2007 Jan;14(1):31-40. doi: 10.1016/j.chembiol.2006.11.005. Chem Biol. 2007. PMID: 17254950

4

Covalent CouN7 enzyme intermediate for acyl group shuttling in aminocoumarin biosynthesis.

Balibar CJ, Garneau-Tsodikova S, Walsh CT. Balibar CJ, et al. Among authors: walsh ct. Chem Biol. 2007 Jun;14(6):679-90. doi: 10.1016/j.chembiol.2007.05.007. Chem Biol. 2007. PMID: 17584615

5

DpgC is a metal- and cofactor-free 3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase in the vancomycin biosynthetic pathway.

Tseng CC, Vaillancourt FH, Bruner SD, Walsh CT. Tseng CC, et al. Among authors: walsh ct. Chem Biol. 2004 Sep;11(9):1195-203. doi: 10.1016/j.chembiol.2004.06.012. Chem Biol. 2004. PMID: 15380180

6

SyrB2 in syringomycin E biosynthesis is a nonheme FeII alpha-ketoglutarate- and O2-dependent halogenase.

Vaillancourt FH, Yin J, Walsh CT. Vaillancourt FH, et al. Among authors: walsh ct. Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10111-6. doi: 10.1073/pnas.0504412102. Epub 2005 Jul 7. Proc Natl Acad Sci U S A. 2005. PMID: 16002467 Free PMC article.

7

Dichlorination and bromination of a threonyl-S-carrier protein by the non-heme Fe(II) halogenase SyrB2.

Vaillancourt FH, Vosburg DA, Walsh CT. Vaillancourt FH, et al. Among authors: walsh ct. Chembiochem. 2006 May;7(5):748-52. doi: 10.1002/cbic.200500480. Chembiochem. 2006. PMID: 16528784 No abstract available.

8

Two interconverting Fe(IV) intermediates in aliphatic chlorination by the halogenase CytC3.

Galonić DP, Barr EW, Walsh CT, Bollinger JM Jr, Krebs C. Galonić DP, et al. Among authors: walsh ct. Nat Chem Biol. 2007 Feb;3(2):113-6. doi: 10.1038/nchembio856. Epub 2007 Jan 14. Nat Chem Biol. 2007. PMID: 17220900

9

Characterization of the aminocarboxycyclopropane-forming enzyme CmaC.

Kelly WL, Boyne MT 2nd, Yeh E, Vosburg DA, Galonić DP, Kelleher NL, Walsh CT. Kelly WL, et al. Among authors: walsh ct. Biochemistry. 2007 Jan 16;46(2):359-68. doi: 10.1021/bi061930j. Biochemistry. 2007. PMID: 17209546

10

Halogenation of unactivated carbon centers in natural product biosynthesis: trichlorination of leucine during barbamide biosynthesis.

Galonić DP, Vaillancourt FH, Walsh CT. Galonić DP, et al. Among authors: walsh ct. J Am Chem Soc. 2006 Mar 29;128(12):3900-1. doi: 10.1021/ja060151n. J Am Chem Soc. 2006. PMID: 16551084

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