Neve RL - Search Results

1

Dysfunction of amyloid precursor protein signaling in neurons leads to DNA synthesis and apoptosis.

Neve RL, McPhie DL. Neve RL, et al. Biochim Biophys Acta. 2007 Apr;1772(4):430-7. doi: 10.1016/j.bbadis.2006.10.008. Epub 2006 Oct 18. Biochim Biophys Acta. 2007. PMID: 17113271 Free PMC article. Review.

2

DNA synthesis and neuronal apoptosis caused by familial Alzheimer disease mutants of the amyloid precursor protein are mediated by the p21 activated kinase PAK3.

McPhie DL, Coopersmith R, Hines-Peralta A, Chen Y, Ivins KJ, Manly SP, Kozlowski MR, Neve KA, Neve RL. McPhie DL, et al. Among authors: neve rl, neve ka. J Neurosci. 2003 Jul 30;23(17):6914-27. doi: 10.1523/JNEUROSCI.23-17-06914.2003. J Neurosci. 2003. PMID: 12890786 Free PMC article.

3

APP-BP1 mediates APP-induced apoptosis and DNA synthesis and is increased in Alzheimer's disease brain.

Chen Y, Liu W, McPhie DL, Hassinger L, Neve RL. Chen Y, et al. Among authors: neve rl. J Cell Biol. 2003 Oct 13;163(1):27-33. doi: 10.1083/jcb.200304003. J Cell Biol. 2003. PMID: 14557245 Free PMC article.

4

The cell cycle as a therapeutic target for Alzheimer's disease.

Neve RL, McPhie DL. Neve RL, et al. Pharmacol Ther. 2006 Jul;111(1):99-113. doi: 10.1016/j.pharmthera.2005.09.005. Epub 2005 Nov 7. Pharmacol Ther. 2006. PMID: 16274748 Review.

5

Rab5 mediates an amyloid precursor protein signaling pathway that leads to apoptosis.

Laifenfeld D, Patzek LJ, McPhie DL, Chen Y, Levites Y, Cataldo AM, Neve RL. Laifenfeld D, et al. Among authors: neve rl. J Neurosci. 2007 Jul 4;27(27):7141-53. doi: 10.1523/JNEUROSCI.4599-06.2007. J Neurosci. 2007. PMID: 17611268 Free PMC article.

6

Transgenic mice expressing APP-C100 in the brain.

Neve RL, Boyce FM, McPhie DL, Greenan J, Oster-Granite ML. Neve RL, et al. Neurobiol Aging. 1996 Mar-Apr;17(2):191-203. doi: 10.1016/0197-4580(95)02074-8. Neurobiol Aging. 1996. PMID: 8744400

7

Neuronal expression of beta-amyloid precursor protein Alzheimer mutations causes intracellular accumulation of a C-terminal fragment containing both the amyloid beta and cytoplasmic domains.

McPhie DL, Lee RK, Eckman CB, Olstein DH, Durham SP, Yager D, Younkin SG, Wurtman RJ, Neve RL. McPhie DL, et al. Among authors: neve rl. J Biol Chem. 1997 Oct 3;272(40):24743-6. doi: 10.1074/jbc.272.40.24743. J Biol Chem. 1997. PMID: 9312066 Free article.

8

Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis.

Bursztajn S, DeSouza R, McPhie DL, Berman SA, Shioi J, Robakis NK, Neve RL. Bursztajn S, et al. Among authors: neve rl. J Neurosci. 1998 Dec 1;18(23):9790-9. doi: 10.1523/JNEUROSCI.18-23-09790.1998. J Neurosci. 1998. PMID: 9822738 Free PMC article.

9

The amyloid precursor protein-binding protein APP-BP1 drives the cell cycle through the S-M checkpoint and causes apoptosis in neurons.

Chen Y, McPhie DL, Hirschberg J, Neve RL. Chen Y, et al. Among authors: neve rl. J Biol Chem. 2000 Mar 24;275(12):8929-35. doi: 10.1074/jbc.275.12.8929. J Biol Chem. 2000. PMID: 10722740 Free article.

10

Alzheimer's disease: a dysfunction of the amyloid precursor protein(1).

Neve RL, McPhie DL, Chen Y. Neve RL, et al. Brain Res. 2000 Dec 15;886(1-2):54-66. doi: 10.1016/s0006-8993(00)02869-9. Brain Res. 2000. PMID: 11119687 Review.

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