Dragin N - Search Results

1

Enhanced cadmium-induced testicular necrosis and renal proximal tubule damage caused by gene-dose increase in a Slc39a8-transgenic mouse line.

Wang B, Schneider SN, Dragin N, Girijashanker K, Dalton TP, He L, Miller ML, Stringer KF, Soleimani M, Richardson DD, Nebert DW. Wang B, et al. Among authors: dragin n. Am J Physiol Cell Physiol. 2007 Apr;292(4):C1523-35. doi: 10.1152/ajpcell.00409.2006. Epub 2006 Nov 15. Am J Physiol Cell Physiol. 2007. PMID: 17108009 Free article.

2

Theophylline pharmacokinetics: comparison of Cyp1a1(-/-) and Cyp1a2(-/-) knockout mice, humanized hCYP1A1_1A2 knock-in mice lacking either the mouse Cyp1a1 or Cyp1a2 gene, and Cyp1(+/+) wild-type mice.

Derkenne S, Curran CP, Shertzer HG, Dalton TP, Dragin N, Nebert DW. Derkenne S, et al. Among authors: dragin n. Pharmacogenet Genomics. 2005 Jul;15(7):503-11. doi: 10.1097/01.fpc.0000167326.00411.50. Pharmacogenet Genomics. 2005. PMID: 15970798

3

Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate.

Uno S, Dalton TP, Dragin N, Curran CP, Derkenne S, Miller ML, Shertzer HG, Gonzalez FJ, Nebert DW. Uno S, et al. Among authors: dragin n. Mol Pharmacol. 2006 Apr;69(4):1103-14. doi: 10.1124/mol.105.021501. Epub 2005 Dec 23. Mol Pharmacol. 2006. PMID: 16377763

4

For dioxin-induced birth defects, mouse or human CYP1A2 in maternal liver protects whereas mouse CYP1A1 and CYP1B1 are inconsequential.

Dragin N, Dalton TP, Miller ML, Shertzer HG, Nebert DW. Dragin N, et al. J Biol Chem. 2006 Jul 7;281(27):18591-600. doi: 10.1074/jbc.M601159200. Epub 2006 Apr 24. J Biol Chem. 2006. PMID: 16636061 Free article.

5

Generation of 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-) mouse line.

Dragin N, Uno S, Wang B, Dalton TP, Nebert DW. Dragin N, et al. Biochem Biophys Res Commun. 2007 Aug 3;359(3):635-42. doi: 10.1016/j.bbrc.2007.05.202. Epub 2007 Jun 6. Biochem Biophys Res Commun. 2007. PMID: 17560947 Free PMC article.

6

Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract.

Uno S, Dragin N, Miller ML, Dalton TP, Gonzalez FJ, Nebert DW. Uno S, et al. Among authors: dragin n. Free Radic Biol Med. 2008 Feb 15;44(4):570-83. doi: 10.1016/j.freeradbiomed.2007.10.044. Epub 2007 Nov 12. Free Radic Biol Med. 2008. PMID: 17997381 Free PMC article.

7

Oral benzo[a]pyrene-induced cancer: two distinct types in different target organs depend on the mouse Cyp1 genotype.

Shi Z, Dragin N, Miller ML, Stringer KF, Johansson E, Chen J, Uno S, Gonzalez FJ, Rubio CA, Nebert DW. Shi Z, et al. Among authors: dragin n. Int J Cancer. 2010 Nov 15;127(10):2334-50. doi: 10.1002/ijc.25222. Int J Cancer. 2010. PMID: 20127859 Free PMC article.

8

Organ-specific roles of CYP1A1 during detoxication of dietary benzo[a]pyrene.

Shi Z, Dragin N, Gálvez-Peralta M, Jorge-Nebert LF, Miller ML, Wang B, Nebert DW. Shi Z, et al. Among authors: dragin n. Mol Pharmacol. 2010 Jul;78(1):46-57. doi: 10.1124/mol.110.063438. Epub 2010 Apr 6. Mol Pharmacol. 2010. PMID: 20371670 Free PMC article.

9

Naphthalene toxicity in mice and aryl hydrocarbon receptor-mediated CYPs.

Genter MB, Marlowe J, Kevin Kerzee J, Dragin N, Puga A, Dalton TP, Nebert DW. Genter MB, et al. Among authors: dragin n. Biochem Biophys Res Commun. 2006 Sep 15;348(1):120-3. doi: 10.1016/j.bbrc.2006.07.025. Epub 2006 Jul 14. Biochem Biophys Res Commun. 2006. PMID: 16876762

10

Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype.

Jiang Z, Dragin N, Jorge-Nebert LF, Martin MV, Guengerich FP, Aklillu E, Ingelman-Sundberg M, Hammons GJ, Lyn-Cook BD, Kadlubar FF, Saldana SN, Sorter M, Vinks AA, Nassr N, von Richter O, Jin L, Nebert DW. Jiang Z, et al. Among authors: dragin n. Pharmacogenet Genomics. 2006 May;16(5):359-67. doi: 10.1097/01.fpc.0000204994.99429.46. Pharmacogenet Genomics. 2006. PMID: 16609368

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