Jenkins BJ - Search Results

1

Pathologic consequences of STAT3 hyperactivation by IL-6 and IL-11 during hematopoiesis and lymphopoiesis.

Jenkins BJ, Roberts AW, Greenhill CJ, Najdovska M, Lundgren-May T, Robb L, Grail D, Ernst M. Jenkins BJ, et al. Blood. 2007 Mar 15;109(6):2380-8. doi: 10.1182/blood-2006-08-040352. Epub 2006 Nov 2. Blood. 2007. PMID: 17082315 Free article.

2

Saturation mutagenesis of the beta subunit of the human granulocyte-macrophage colony-stimulating factor receptor shows clustering of constitutive mutations, activation of ERK MAP kinase and STAT pathways, and differential beta subunit tyrosine phosphorylation.

Jenkins BJ, Blake TJ, Gonda TJ. Jenkins BJ, et al. Blood. 1998 Sep 15;92(6):1989-2002. Blood. 1998. PMID: 9731057 Free article.

3

Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice.

Tebbutt NC, Giraud AS, Inglese M, Jenkins B, Waring P, Clay FJ, Malki S, Alderman BM, Grail D, Hollande F, Heath JK, Ernst M. Tebbutt NC, et al. Nat Med. 2002 Oct;8(10):1089-97. doi: 10.1038/nm763. Epub 2002 Sep 9. Nat Med. 2002. PMID: 12219085

4

Hematopoietic abnormalities in mice deficient in gp130-mediated STAT signaling.

Jenkins BJ, Quilici C, Roberts AW, Grail D, Dunn AR, Ernst M. Jenkins BJ, et al. Exp Hematol. 2002 Nov;30(11):1248-56. doi: 10.1016/s0301-472x(02)00929-3. Exp Hematol. 2002. PMID: 12423677 Free article.

5

Acquiring signalling specificity from the cytokine receptor gp130.

Ernst M, Jenkins BJ. Ernst M, et al. Among authors: jenkins bj. Trends Genet. 2004 Jan;20(1):23-32. doi: 10.1016/j.tig.2003.11.003. Trends Genet. 2004. PMID: 14698616 Review.

6

Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130.

Judd LM, Alderman BM, Howlett M, Shulkes A, Dow C, Moverley J, Grail D, Jenkins BJ, Ernst M, Giraud AS. Judd LM, et al. Among authors: jenkins bj. Gastroenterology. 2004 Jan;126(1):196-207. doi: 10.1053/j.gastro.2003.10.066. Gastroenterology. 2004. PMID: 14699500

7

Imbalanced gp130-dependent signaling in macrophages alters macrophage colony-stimulating factor responsiveness via regulation of c-fms expression.

Jenkins BJ, Grail D, Inglese M, Quilici C, Bozinovski S, Wong P, Ernst M. Jenkins BJ, et al. Mol Cell Biol. 2004 Feb;24(4):1453-63. doi: 10.1128/MCB.24.4.1453-1463.2004. Mol Cell Biol. 2004. PMID: 14749363 Free PMC article.

8

Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways.

Sims NA, Jenkins BJ, Quinn JM, Nakamura A, Glatt M, Gillespie MT, Ernst M, Martin TJ. Sims NA, et al. Among authors: jenkins bj. J Clin Invest. 2004 Feb;113(3):379-89. doi: 10.1172/JCI19872. J Clin Invest. 2004. PMID: 14755335 Free PMC article.

9

The threshold of gp130-dependent STAT3 signaling is critical for normal regulation of hematopoiesis.

Jenkins BJ, Roberts AW, Najdovska M, Grail D, Ernst M. Jenkins BJ, et al. Blood. 2005 May 1;105(9):3512-20. doi: 10.1182/blood-2004-09-3751. Epub 2005 Jan 13. Blood. 2005. PMID: 15650055 Free article.

10

Interleukin-11 receptor signaling is required for normal bone remodeling.

Sims NA, Jenkins BJ, Nakamura A, Quinn JM, Li R, Gillespie MT, Ernst M, Robb L, Martin TJ. Sims NA, et al. Among authors: jenkins bj. J Bone Miner Res. 2005 Jul;20(7):1093-102. doi: 10.1359/JBMR.050209. Epub 2005 Feb 14. J Bone Miner Res. 2005. PMID: 15940362 Free article.

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