Manta S - Search Results

1

Fluoro-ketopyranosyl nucleosides: synthesis and biological evaluation of 3-fluoro-2-keto-beta-D-glucopyranosyl derivatives of N4-benzoyl cytosine.

Manta S, Agelis G, Botić T, Cencic A, Komiotis D. Manta S, et al. Bioorg Med Chem. 2007 Jan 15;15(2):980-7. doi: 10.1016/j.bmc.2006.10.033. Epub 2006 Oct 19. Bioorg Med Chem. 2007. PMID: 17079149

2

Unsaturated fluoro-ketopyranosyl nucleosides: synthesis and biological evaluation of 3-fluoro-4-keto-beta-d-glucopyranosyl derivatives of N(4)-benzoyl cytosine and N(6)-benzoyl adenine.

Manta S, Agelis G, Botić T, Cencic A, Komiotis D. Manta S, et al. Eur J Med Chem. 2008 Feb;43(2):420-8. doi: 10.1016/j.ejmech.2007.04.001. Epub 2007 Apr 25. Eur J Med Chem. 2008. PMID: 17548129

3

A concise synthesis of 3-fluoro-5-thio-xylo- and glucopyranoses, useful precursors towards their corresponding pyranonucleoside derivatives.

Tsoukala E, Manta S, Tzioumaki N, Agelis G, Komiotis D. Tsoukala E, et al. Among authors: manta s. Carbohydr Res. 2008 May 5;343(6):1099-103. doi: 10.1016/j.carres.2008.02.004. Epub 2008 Feb 10. Carbohydr Res. 2008. PMID: 18313037

4

Dideoxy fluoro-ketopyranosyl nucleosides as potent antiviral agents: synthesis and biological evaluation of 2,3- and 3,4-dideoxy-3-fluoro-4- and -2-keto-beta-d-glucopyranosyl derivatives of N(4)-benzoyl cytosine.

Manta S, Tsoukala E, Tzioumaki N, Goropevsek A, Pamulapati RT, Cencic A, Balzarini J, Komiotis D. Manta S, et al. Eur J Med Chem. 2009 Jun;44(6):2696-704. doi: 10.1016/j.ejmech.2009.01.020. Epub 2009 Jan 29. Eur J Med Chem. 2009. PMID: 19246130 Free PMC article.

5

Competitive inhibition of human poly(A)-specific ribonuclease (PARN) by synthetic fluoro-pyranosyl nucleosides.

Balatsos NA, Vlachakis D, Maragozidis P, Manta S, Anastasakis D, Kyritsis A, Vlassi M, Komiotis D, Stathopoulos C. Balatsos NA, et al. Among authors: manta s. Biochemistry. 2009 Jul 7;48(26):6044-51. doi: 10.1021/bi900236k. Biochemistry. 2009. PMID: 19472977

6

Synthesis, antiviral and cytostatic evaluation of unsaturated exomethylene and keto D-lyxopyranonucleoside analogues.

Tzioumaki N, Tsoukala E, Manta S, Agelis G, Balzarini J, Komiotis D. Tzioumaki N, et al. Among authors: manta s. Arch Pharm (Weinheim). 2009 Jun;342(6):353-60. doi: 10.1002/ardp.200900004. Arch Pharm (Weinheim). 2009. PMID: 19479749

7

Unsaturated dideoxy fluoro-ketopyranosyl nucleosides as new cytostatic agents: a convenient synthesis of 2,6-dideoxy-3-fluoro-4-keto-beta-D-glucopyranosyl analogues of uracil, 5-fluorouracil, thymine, N4-benzoyl cytosine and N6-benzoyl adenine.

Manta S, Tzioumaki N, Tsoukala E, Panagiotopoulou A, Pelecanou M, Balzarini J, Komiotis D. Manta S, et al. Eur J Med Chem. 2009 Nov;44(11):4764-71. doi: 10.1016/j.ejmech.2009.06.013. Epub 2009 Jun 18. Eur J Med Chem. 2009. PMID: 19595489

8

Synthesis of 4,6-dideoxy-3-fluoro-2-keto-beta-D-glucopyranosyl analogues of 5-fluorouracil, N6-benzoyl adenine, uracil, thymine, N4-benzoyl cytosine and evaluation of their antitumor activities.

Manta S, Tsoukala E, Tzioumaki N, Kiritsis C, Balzarini J, Komiotis D. Manta S, et al. Bioorg Chem. 2010 Apr;38(2):48-55. doi: 10.1016/j.bioorg.2009.11.001. Epub 2009 Nov 20. Bioorg Chem. 2010. PMID: 20018340

9

1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies.

Tsirkone VG, Tsoukala E, Lamprakis C, Manta S, Hayes JM, Skamnaki VT, Drakou C, Zographos SE, Komiotis D, Leonidas DD. Tsirkone VG, et al. Among authors: manta s. Bioorg Med Chem. 2010 May 15;18(10):3413-25. doi: 10.1016/j.bmc.2010.04.004. Epub 2010 Apr 7. Bioorg Med Chem. 2010. PMID: 20430629

10

Synthesis of 3-fluoro-6-S-(2-S-pyridyl) nucleosides as potential lead cytostatic agents.

Tsoukala E, Tzioumaki N, Manta S, Riga A, Balzarini J, Komiotis D. Tsoukala E, et al. Among authors: manta s. Bioorg Chem. 2010 Dec;38(6):285-93. doi: 10.1016/j.bioorg.2010.08.001. Epub 2010 Aug 17. Bioorg Chem. 2010. PMID: 20817215 Free PMC article.

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