van Oeveren A - Search Results

1

Structure of the ligand-binding domain (LBD) of human androgen receptor in complex with a selective modulator LGD2226.

Wang F, Liu XQ, Li H, Liang KN, Miner JN, Hong M, Kallel EA, van Oeveren A, Zhi L, Jiang T. Wang F, et al. Among authors: van oeveren a. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Nov 1;62(Pt 11):1067-71. doi: 10.1107/S1744309106039340. Epub 2006 Oct 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 17077481 Free PMC article.

2

An orally active selective androgen receptor modulator is efficacious on bone, muscle, and sex function with reduced impact on prostate.

Miner JN, Chang W, Chapman MS, Finn PD, Hong MH, López FJ, Marschke KB, Rosen J, Schrader W, Turner R, van Oeveren A, Viveros H, Zhi L, Negro-Vilar A. Miner JN, et al. Among authors: van oeveren a. Endocrinology. 2007 Jan;148(1):363-73. doi: 10.1210/en.2006-0793. Epub 2006 Oct 5. Endocrinology. 2007. PMID: 17023534

3

Discovery of 6-N,N-bis(2,2,2-trifluoroethyl)amino- 4-trifluoromethylquinolin-2(1H)-one as a novel selective androgen receptor modulator.

van Oeveren A, Motamedi M, Mani NS, Marschke KB, López FJ, Schrader WT, Negro-Vilar A, Zhi L. van Oeveren A, et al. J Med Chem. 2006 Oct 19;49(21):6143-6. doi: 10.1021/jm060792t. J Med Chem. 2006. PMID: 17034117

4

Novel selective androgen receptor modulators: SAR studies on 6-bisalkylamino-2-quinolinones.

van Oeveren A, Motamedi M, Martinborough E, Zhao S, Shen Y, West S, Chang W, Kallel A, Marschke KB, López FJ, Negro-Vilar A, Zhi L. van Oeveren A, et al. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1527-31. doi: 10.1016/j.bmcl.2007.01.001. Epub 2007 Jan 8. Bioorg Med Chem Lett. 2007. PMID: 17267219

5

Discovery of an androgen receptor modulator pharmacophore based on 2-quinolinones.

van Oeveren A, Pio BA, Tegley CM, Higuchi RI, Wu M, Jones TK, Marschke KB, Negro-Vilar A, Zhi L. van Oeveren A, et al. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1523-6. doi: 10.1016/j.bmcl.2007.01.007. Epub 2007 Jan 13. Bioorg Med Chem Lett. 2007. PMID: 17257838

6

Discovery of a novel series of nonsteroidal androgen receptor modulators: 5- or 6-oxachrysen-2-ones.

Zhao S, Shen Y, van Oeveren A, Marschke KB, Zhi L. Zhao S, et al. Among authors: van oeveren a. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3431-5. doi: 10.1016/j.bmcl.2008.03.085. Epub 2008 Apr 8. Bioorg Med Chem Lett. 2008. PMID: 18442912

7

Combination treatment with a selective androgen receptor modulator q(SARM) and a bisphosphonate has additive effects in osteopenic female rats.

Vajda EG, Hogue A, Griffiths KN, Chang WY, Burnett K, Chen Y, Marschke K, Mais DE, Pedram B, Shen Y, van Oeveren A, Zhi L, López FJ, Meglasson MD. Vajda EG, et al. Among authors: van oeveren a. J Bone Miner Res. 2009 Feb;24(2):231-40. doi: 10.1359/jbmr.081007. J Bone Miner Res. 2009. PMID: 18847323 Free article.

8

A tissue-selective nonsteroidal progesterone receptor modulator: 7,9-difluoro-5-(3-methylcyclohex-2-enyl)-2,2,4-trimethyl-1,2-dihydrochromeno[3,4-f]quinoline.

Pedram B, van Oeveren A, Mais DE, Marschke KB, Verbost PM, Groen MB, Zhi L. Pedram B, et al. Among authors: van oeveren a. J Med Chem. 2008 Jul 10;51(13):3696-9. doi: 10.1021/jm8004256. Epub 2008 Jun 14. J Med Chem. 2008. PMID: 18553958

9

Synthesis and cytotoxicity of novel lignans.

Middel O, Woerdenbag HJ, van Uden W, van Oeveren A, Jansen JF, Feringa BL, Konings AW, Pras N, Kellogg RM. Middel O, et al. Among authors: van oeveren a, van uden w. J Med Chem. 1995 Jun 9;38(12):2112-8. doi: 10.1021/jm00012a010. J Med Chem. 1995. PMID: 7783142 Free article.

10

Asymmetric Synthesis of 5-Substituted gamma-Lactones and Butenolides via Nucleophilic Additions to Oxycarbenium Ions Derived from 5(R)-(Menthyloxy)-4(R)- (phenylsulfanyl)-2(3H)-dihydrofuranone.

van Oeveren A, Feringa BL. van Oeveren A, et al. J Org Chem. 1996 May 3;61(9):2920-2921. doi: 10.1021/jo960078r. J Org Chem. 1996. PMID: 11667142 No abstract available.

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