Kopan R - Search Results

1

Quantitative dissection of the Notch:CSL interaction: insights into the Notch-mediated transcriptional switch.

Lubman OY, Ilagan MX, Kopan R, Barrick D. Lubman OY, et al. Among authors: kopan r. J Mol Biol. 2007 Jan 19;365(3):577-89. doi: 10.1016/j.jmb.2006.09.071. Epub 2006 Oct 3. J Mol Biol. 2007. PMID: 17070841 Free PMC article.

2

Thermodynamic analysis of the CSL x Notch interaction: distribution of binding energy of the Notch RAM region to the CSL beta-trefoil domain and the mode of competition with the viral transactivator EBNA2.

Johnson SE, Ilagan MX, Kopan R, Barrick D. Johnson SE, et al. Among authors: kopan r. J Biol Chem. 2010 Feb 26;285(9):6681-92. doi: 10.1074/jbc.M109.019968. Epub 2009 Dec 22. J Biol Chem. 2010. PMID: 20028974 Free PMC article.

3

Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes.

Arnett KL, Hass M, McArthur DG, Ilagan MX, Aster JC, Kopan R, Blacklow SC. Arnett KL, et al. Among authors: kopan r. Nat Struct Mol Biol. 2010 Nov;17(11):1312-7. doi: 10.1038/nsmb.1938. Epub 2010 Oct 24. Nat Struct Mol Biol. 2010. PMID: 20972443 Free PMC article.

4

Monitoring Notch activation in cultured mammalian cells: transcriptional reporter assays.

Ilagan MX, Kopan R. Ilagan MX, et al. Among authors: kopan r. Methods Mol Biol. 2014;1187:143-54. doi: 10.1007/978-1-4939-1139-4_11. Methods Mol Biol. 2014. PMID: 25053487 Review.

5

The Notch transcription activation complex makes its move.

Barrick D, Kopan R. Barrick D, et al. Among authors: kopan r. Cell. 2006 Mar 10;124(5):883-5. doi: 10.1016/j.cell.2006.02.028. Cell. 2006. PMID: 16530033 Free article.

6

Monitoring Notch activation in cultured mammalian cells: luciferase complementation imaging assays.

Ilagan MX, Kopan R. Ilagan MX, et al. Among authors: kopan r. Methods Mol Biol. 2014;1187:155-68. doi: 10.1007/978-1-4939-1139-4_12. Methods Mol Biol. 2014. PMID: 25053488

7

Anchoring notch genetics and biochemistry; structural analysis of the ankyrin domain sheds light on existing data.

Lubman OY, Korolev SV, Kopan R. Lubman OY, et al. Among authors: kopan r. Mol Cell. 2004 Mar 12;13(5):619-26. doi: 10.1016/s1097-2765(04)00120-0. Mol Cell. 2004. PMID: 15023333 Free article. Review.

8

The crystal structure of a partial mouse Notch-1 ankyrin domain: repeats 4 through 7 preserve an ankyrin fold.

Lubman OY, Kopan R, Waksman G, Korolev S. Lubman OY, et al. Among authors: kopan r. Protein Sci. 2005 May;14(5):1274-81. doi: 10.1110/ps.041184105. Epub 2005 Mar 31. Protein Sci. 2005. PMID: 15802643 Free PMC article.

9

Gamma-secretase: proteasome of the membrane?

Kopan R, Ilagan MX. Kopan R, et al. Nat Rev Mol Cell Biol. 2004 Jun;5(6):499-504. doi: 10.1038/nrm1406. Nat Rev Mol Cell Biol. 2004. PMID: 15173829 Review. No abstract available.

10

Structural analysis uncovers lipid-binding properties of Notch ligands.

Chillakuri CR, Sheppard D, Ilagan MX, Holt LR, Abbott F, Liang S, Kopan R, Handford PA, Lea SM. Chillakuri CR, et al. Among authors: kopan r. Cell Rep. 2013 Nov 27;5(4):861-7. doi: 10.1016/j.celrep.2013.10.029. Epub 2013 Nov 14. Cell Rep. 2013. PMID: 24239355 Free PMC article.

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