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A promoter haplotype of the inositol monophosphatase 2 gene (IMPA2) at 18p11.2 confers a possible risk for bipolar disorder by enhancing transcription.
Ohnishi T, Yamada K, Ohba H, Iwayama Y, Toyota T, Hattori E, Inada T, Kunugi H, Tatsumi M, Ozaki N, Iwata N, Sakamoto K, Iijima Y, Iwata Y, Tsuchiya KJ, Sugihara G, Nanko S, Osumi N, Detera-Wadleigh SD, Kato T, Yoshikawa T. Ohnishi T, et al. Neuropsychopharmacology. 2007 Aug;32(8):1727-37. doi: 10.1038/sj.npp.1301307. Epub 2007 Jan 24. Neuropsychopharmacology. 2007. PMID: 17251911
Human myo-inositol monophosphatase 2 rescues the nematode thermotaxis mutant ttx-7 more efficiently than IMPA1: functional and evolutionary considerations of the two mammalian myo-inositol monophosphatase genes.
Ohnishi T, Tanizawa Y, Watanabe A, Nakamura T, Ohba H, Hirata H, Kaneda C, Iwayama Y, Arimoto T, Watanabe K, Mori I, Yoshikawa T. Ohnishi T, et al. J Neurochem. 2013 Mar;124(5):685-94. doi: 10.1111/jnc.12112. Epub 2012 Dec 26. J Neurochem. 2013. PMID: 23205734 Free article.
Distinguishable haplotype blocks in the HTR3A and HTR3B region in the Japanese reveal evidence of association of HTR3B with female major depression.
Yamada K, Hattori E, Iwayama Y, Ohnishi T, Ohba H, Toyota T, Takao H, Minabe Y, Nakatani N, Higuchi T, Detera-Wadleigh SD, Yoshikawa T. Yamada K, et al. Among authors: ohnishi t. Biol Psychiatry. 2006 Jul 15;60(2):192-201. doi: 10.1016/j.biopsych.2005.11.008. Epub 2006 Feb 17. Biol Psychiatry. 2006. PMID: 16487942
Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia.
Yamada K, Gerber DJ, Iwayama Y, Ohnishi T, Ohba H, Toyota T, Aruga J, Minabe Y, Tonegawa S, Yoshikawa T. Yamada K, et al. Among authors: ohnishi t. Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2815-20. doi: 10.1073/pnas.0610765104. Epub 2007 Feb 20. Proc Natl Acad Sci U S A. 2007. PMID: 17360599 Free PMC article.
[Molecular genetic approach to depression from animal models].
Yoshikawa T, Ohnishi T. Yoshikawa T, et al. Among authors: ohnishi t. Nihon Yakurigaku Zasshi. 2005 Jan;125(1):25-32. doi: 10.1254/fpj.125.25. Nihon Yakurigaku Zasshi. 2005. PMID: 15738618 Review. Japanese. No abstract available.
1,906 results