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Substrate cleavage profiling suggests a distinct function of Bacteroides fragilis metalloproteinases (fragilysin and metalloproteinase II) at the microbiome-inflammation-cancer interface.
Shiryaev SA, Remacle AG, Chernov AV, Golubkov VS, Motamedchaboki K, Muranaka N, Dambacher CM, Capek P, Kukreja M, Kozlov IA, Perucho M, Cieplak P, Strongin AY. Shiryaev SA, et al. Among authors: kozlov ia. J Biol Chem. 2013 Nov 29;288(48):34956-67. doi: 10.1074/jbc.M113.516153. Epub 2013 Oct 21. J Biol Chem. 2013. PMID: 24145028 Free PMC article.
A method for rapid protease substrate evaluation and optimization.
Kozlov IA, Melnyk PC, Zhao C, Hachmann JP, Shevchenko V, Srinivasan A, Barker DL, Lebl M. Kozlov IA, et al. Comb Chem High Throughput Screen. 2006 Jul;9(6):481-7. doi: 10.2174/138620706777698535. Comb Chem High Throughput Screen. 2006. PMID: 16842230
227 results