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Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch.
Giuriato S, Ryeom S, Fan AC, Bachireddy P, Lynch RC, Rioth MJ, van Riggelen J, Kopelman AM, Passegué E, Tang F, Folkman J, Felsher DW. Giuriato S, et al. Among authors: van riggelen j. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16266-71. doi: 10.1073/pnas.0608017103. Epub 2006 Oct 20. Proc Natl Acad Sci U S A. 2006. PMID: 17056717 Free PMC article.
Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction.
Choi PS, van Riggelen J, Gentles AJ, Bachireddy P, Rakhra K, Adam SJ, Plevritis SK, Felsher DW. Choi PS, et al. Among authors: van riggelen j. Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17432-7. doi: 10.1073/pnas.1107303108. Epub 2011 Oct 3. Proc Natl Acad Sci U S A. 2011. PMID: 21969595 Free PMC article.
Myc and a Cdk2 senescence switch.
van Riggelen J, Felsher DW. van Riggelen J, et al. Nat Cell Biol. 2010 Jan;12(1):7-9. doi: 10.1038/ncb0110-7. Nat Cell Biol. 2010. PMID: 20027199
19 results