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Acylguanidines as small-molecule beta-secretase inhibitors.
J Med Chem. 2006 Oct 19;49(21):6158-61. doi: 10.1021/jm0607451.
J Med Chem. 2006.
PMID: 17034121
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1' substrate binding pocket.
Jennings LD, Cole DC, Stock JR, Sukhdeo MN, Ellingboe JW, Cowling R, Jin G, Manas ES, Fan KY, Malamas MS, Harrison BL, Jacobsen S, Chopra R, Lohse PA, Moore WJ, O'Donnell MM, Hu Y, Robichaud AJ, Turner MJ, Wagner E, Bard J.
Jennings LD, et al. Among authors: sukhdeo mn.
Bioorg Med Chem Lett. 2008 Jan 15;18(2):767-71. doi: 10.1016/j.bmcl.2007.11.043. Epub 2007 Nov 17.
Bioorg Med Chem Lett. 2008.
PMID: 18068983
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Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction.
Jennings LD, Foreman KW, Rush TS 3rd, Tsao DH, Mosyak L, Li Y, Sukhdeo MN, Ding W, Dushin EG, Kenny CH, Moghazeh SL, Petersen PJ, Ruzin AV, Tuckman M, Sutherland AG.
Jennings LD, et al. Among authors: sukhdeo mn.
Bioorg Med Chem Lett. 2004 Mar 22;14(6):1427-31. doi: 10.1016/j.bmcl.2004.01.028.
Bioorg Med Chem Lett. 2004.
PMID: 15006376
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Combinatorial synthesis of substituted 3-(2-indolyl)piperidines and 2-phenyl indoles as inhibitors of ZipA-FtsZ interaction.
Jennings LD, Foreman KW, Rush TS 3rd, Tsao DH, Mosyak L, Kincaid SL, Sukhdeo MN, Sutherland AG, Ding W, Kenny CH, Sabus CL, Liu H, Dushin EG, Moghazeh SL, Labthavikul P, Petersen PJ, Tuckman M, Haney SA, Ruzin AV.
Jennings LD, et al. Among authors: sukhdeo mn.
Bioorg Med Chem. 2004 Oct 1;12(19):5115-31. doi: 10.1016/j.bmc.2004.07.031.
Bioorg Med Chem. 2004.
PMID: 15351395
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