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Acylguanidines as small-molecule beta-secretase inhibitors.
J Med Chem. 2006 Oct 19;49(21):6158-61. doi: 10.1021/jm0607451.
J Med Chem. 2006.
PMID: 17034121
Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors.
Malamas MS, Barnes K, Hui Y, Johnson M, Lovering F, Condon J, Fobare W, Solvibile W, Turner J, Hu Y, Manas ES, Fan K, Olland A, Chopra R, Bard J, Pangalos MN, Reinhart P, Robichaud AJ.
Malamas MS, et al.
Bioorg Med Chem Lett. 2010 Apr 1;20(7):2068-73. doi: 10.1016/j.bmcl.2010.02.075. Epub 2010 Feb 23.
Bioorg Med Chem Lett. 2010.
PMID: 20223661
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Identification of potent and selective TACE inhibitors via the S1 pocket.
Condon JS, Joseph-McCarthy D, Levin JI, Lombart HG, Lovering FE, Sun L, Wang W, Xu W, Zhang Y.
Condon JS, et al.
Bioorg Med Chem Lett. 2007 Jan 1;17(1):34-9. doi: 10.1016/j.bmcl.2006.10.004. Epub 2006 Oct 5.
Bioorg Med Chem Lett. 2007.
PMID: 17064892
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Selective inhibitors of tumor progression loci-2 (Tpl2) kinase with potent inhibition of TNF-alpha production in human whole blood.
Wu J, Green N, Hotchandani R, Hu Y, Condon J, Huang A, Kaila N, Li HQ, Guler S, Li W, Tam SY, Wang Q, Pelker J, Marusic S, Hsu S, Perry Hall J, Telliez JB, Cui J, Lin LL.
Wu J, et al.
Bioorg Med Chem Lett. 2009 Jul 1;19(13):3485-8. doi: 10.1016/j.bmcl.2009.05.009. Epub 2009 May 7.
Bioorg Med Chem Lett. 2009.
PMID: 19464884
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