Staelens S - Search Results

1

Development of monoclonal antibodies that inhibit platelet adhesion or aggregation as potential anti-thrombotic drugs.

De Meyer SF, Vanhoorelbeke K, Ulrichts H, Staelens S, Feys HB, Salles I, Fontayne A, Deckmyn H. De Meyer SF, et al. Among authors: staelens s. Cardiovasc Hematol Disord Drug Targets. 2006 Sep;6(3):191-207. doi: 10.2174/187152906778249536. Cardiovasc Hematol Disord Drug Targets. 2006. PMID: 17017902 Review.

2

New approaches for antithrombotic antiplatelet therapies.

Ulrichts H, Vanhoorelbeke K, Van De Walle G, Katsutani S, De Meyer S, Staelens S, Deckmyn H. Ulrichts H, et al. Among authors: staelens s. Curr Med Chem. 2004 Sep;11(17):2261-3. doi: 10.2174/0929867043364630. Curr Med Chem. 2004. PMID: 15379711 Review.

3

Humanization by variable domain resurfacing and grafting on a human IgG4, using a new approach for determination of non-human like surface accessible framework residues based on homology modelling of variable domains.

Staelens S, Desmet J, Ngo TH, Vauterin S, Pareyn I, Barbeaux P, Van Rompaey I, Stassen JM, Deckmyn H, Vanhoorelbeke K. Staelens S, et al. Mol Immunol. 2006 Mar;43(8):1243-57. doi: 10.1016/j.molimm.2005.07.018. Epub 2005 Aug 22. Mol Immunol. 2006. PMID: 16118019

4

Paratope determination of the antithrombotic antibody 82D6A3 based on the crystal structure of its complex with the von Willebrand factor A3-domain.

Staelens S, Hadders MA, Vauterin S, Platteau C, De Maeyer M, Vanhoorelbeke K, Huizinga EG, Deckmyn H. Staelens S, et al. J Biol Chem. 2006 Jan 27;281(4):2225-31. doi: 10.1074/jbc.M508191200. Epub 2005 Nov 28. J Biol Chem. 2006. PMID: 16314412 Free article.

5

The A/T1381 polymorphism in the A1-domain of von Willebrand factor influences the affinity of von Willebrand factor for platelet glycoprotein Ibalpha.

Szántó T, Schlammadinger A, Staelens S, De Meyer SF, Freson K, Pareyn I, Vauterin S, Hársfalvi J, Deckmyn H, Vanhoorelbeke K. Szántó T, et al. Among authors: staelens s. Thromb Haemost. 2007 Jul;98(1):178-85. Thromb Haemost. 2007. PMID: 17598011

6

Coronary artery in-stent stenosis persists despite inhibition of the von Willebrand factor--collagen interaction in baboons.

De Meyer SF, Staelens S, Badenhorst PN, Pieters H, Lamprecht S, Roodt J, Janssens S, Meiring M, Vanhoorelbeke K, Bruwer A, Brown S, Deckmyn H. De Meyer SF, et al. Among authors: staelens s. Thromb Haemost. 2007 Dec;98(6):1343-9. doi: 10.1160/th07-05-0335. Thromb Haemost. 2007. PMID: 18064334

7

Crucial Role for Endothelial Cell α2β1 Integrin Receptor Clustering in Collagen-Induced Angiogenesis.

Turner KR, Adams C, Staelens S, Deckmyn H, San Antonio J. Turner KR, et al. Among authors: staelens s. Anat Rec (Hoboken). 2020 Jun;303(6):1604-1618. doi: 10.1002/ar.24277. Epub 2019 Oct 31. Anat Rec (Hoboken). 2020. PMID: 31581346 Free article.

8

Biodistribution and dosimetry of the PET radioligand [¹⁸F]CHDI-650 in mice for detection of mutant huntingtin aggregates.

Akkermans J, Miranda A, Verhaeghe J, Elvas F, Zajicek F, Bard J, Liu L, Khetarpal V, Doot R, Staelens S, Bertoglio D. Akkermans J, et al. Among authors: staelens s. EJNMMI Res. 2024 Dec 27;14(1):126. doi: 10.1186/s13550-024-01188-1. EJNMMI Res. 2024. PMID: 39729164 Free PMC article.

9

Preclinical validation and kinetic modelling of the SV2A PET ligand [¹⁸F]UCB-J in mice.

Everix L, Elvas F, Miranda Menchaca A, Khetarpal V, Liu L, Bard J, Staelens S, Bertoglio D. Everix L, et al. Among authors: staelens s. J Cereb Blood Flow Metab. 2024 Dec 4:271678X241304923. doi: 10.1177/0271678X241304923. Online ahead of print. J Cereb Blood Flow Metab. 2024. PMID: 39628318 Free PMC article.

10

Imaging Glucose Metabolism and Dopaminergic Dysfunction in Sheep (Ovis aries) Brain Using Positron Emission Tomography Imaging Reveals Abnormalities in OVT73 Huntington's Disease Sheep.

Williams GK, Akkermans J, Lawson M, Syta P, Staelens S, Adhikari MH, Morton AJ, Nitzsche B, Boltze J, Christou C, Bertoglio D, Ahamed M. Williams GK, et al. Among authors: staelens s. ACS Chem Neurosci. 2024 Nov 6;15(21):4082-4091. doi: 10.1021/acschemneuro.4c00561. Epub 2024 Oct 17. ACS Chem Neurosci. 2024. PMID: 39420554

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