Lichtenstein A - Search Results

1

AKT activity regulates the ability of mTOR inhibitors to prevent angiogenesis and VEGF expression in multiple myeloma cells.

Frost P, Shi Y, Hoang B, Lichtenstein A. Frost P, et al. Among authors: lichtenstein a. Oncogene. 2007 Apr 5;26(16):2255-62. doi: 10.1038/sj.onc.1210019. Epub 2006 Oct 2. Oncogene. 2007. PMID: 17016437

2

Role of the AKT kinase in expansion of multiple myeloma clones: effects on cytokine-dependent proliferative and survival responses.

Hsu JH, Shi Y, Hu L, Fisher M, Franke TF, Lichtenstein A. Hsu JH, et al. Among authors: lichtenstein a. Oncogene. 2002 Feb 21;21(9):1391-400. doi: 10.1038/sj.onc.1205194. Oncogene. 2002. PMID: 11857082

3

Interleukin-6 activates phosphoinositol-3' kinase in multiple myeloma tumor cells by signaling through RAS-dependent and, separately, through p85-dependent pathways.

Hsu JH, Shi Y, Frost P, Yan H, Hoang B, Sharma S, Gera J, Lichtenstein A. Hsu JH, et al. Among authors: lichtenstein a. Oncogene. 2004 Apr 22;23(19):3368-75. doi: 10.1038/sj.onc.1207459. Oncogene. 2004. PMID: 15021914

4

In vivo antitumor effects of the mTOR inhibitor CCI-779 against human multiple myeloma cells in a xenograft model.

Frost P, Moatamed F, Hoang B, Shi Y, Gera J, Yan H, Frost P, Gibbons J, Lichtenstein A. Frost P, et al. Among authors: lichtenstein a. Blood. 2004 Dec 15;104(13):4181-7. doi: 10.1182/blood-2004-03-1153. Epub 2004 Aug 10. Blood. 2004. PMID: 15304393 Free article.

5

Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade.

Shi Y, Yan H, Frost P, Gera J, Lichtenstein A. Shi Y, et al. Among authors: lichtenstein a. Mol Cancer Ther. 2005 Oct;4(10):1533-40. doi: 10.1158/1535-7163.MCT-05-0068. Mol Cancer Ther. 2005. PMID: 16227402

6

Mechanism by which mammalian target of rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis.

Yan H, Frost P, Shi Y, Hoang B, Sharma S, Fisher M, Gera J, Lichtenstein A. Yan H, et al. Among authors: lichtenstein a. Cancer Res. 2006 Feb 15;66(4):2305-13. doi: 10.1158/0008-5472.CAN-05-2447. Cancer Res. 2006. PMID: 16489035

7

Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance.

Hoang B, Zhu L, Shi Y, Frost P, Yan H, Sharma S, Sharma S, Goodglick L, Dubinett S, Lichtenstein A. Hoang B, et al. Among authors: lichtenstein a. Blood. 2006 Jun 1;107(11):4484-90. doi: 10.1182/blood-2005-09-3926. Epub 2006 Feb 23. Blood. 2006. PMID: 16497971 Free PMC article.

8

Regulation of D-cyclin translation inhibition in myeloma cells treated with mammalian target of rapamycin inhibitors: rationale for combined treatment with extracellular signal-regulated kinase inhibitors and rapamycin.

Frost P, Shi Y, Hoang B, Gera J, Lichtenstein A. Frost P, et al. Among authors: lichtenstein a. Mol Cancer Ther. 2009 Jan;8(1):83-93. doi: 10.1158/1535-7163.MCT-08-0254. Mol Cancer Ther. 2009. PMID: 19139116 Free PMC article.

9

Effect of autophagy on multiple myeloma cell viability.

Hoang B, Benavides A, Shi Y, Frost P, Lichtenstein A. Hoang B, et al. Among authors: lichtenstein a. Mol Cancer Ther. 2009 Jul;8(7):1974-84. doi: 10.1158/1535-7163.MCT-08-1177. Epub 2009 Jun 9. Mol Cancer Ther. 2009. PMID: 19509276

10

Targeting TORC2 in multiple myeloma with a new mTOR kinase inhibitor.

Hoang B, Frost P, Shi Y, Belanger E, Benavides A, Pezeshkpour G, Cappia S, Guglielmelli T, Gera J, Lichtenstein A. Hoang B, et al. Among authors: lichtenstein a. Blood. 2010 Nov 25;116(22):4560-8. doi: 10.1182/blood-2010-05-285726. Epub 2010 Aug 4. Blood. 2010. PMID: 20686120 Free PMC article.

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