Kleinjan DA - Search Results

1

Long-range downstream enhancers are essential for Pax6 expression.

Kleinjan DA, Seawright A, Mella S, Carr CB, Tyas DA, Simpson TI, Mason JO, Price DJ, van Heyningen V. Kleinjan DA, et al. Dev Biol. 2006 Nov 15;299(2):563-81. doi: 10.1016/j.ydbio.2006.08.060. Epub 2006 Aug 30. Dev Biol. 2006. PMID: 17014839 Free PMC article.

2

New 3' elements control Pax6 expression in the developing pretectum, neural retina and olfactory region.

Griffin C, Kleinjan DA, Doe B, van Heyningen V. Griffin C, et al. Among authors: kleinjan da. Mech Dev. 2002 Mar;112(1-2):89-100. doi: 10.1016/s0925-4773(01)00646-3. Mech Dev. 2002. PMID: 11850181 Free article.

3

Characterization of a novel gene adjacent to PAX6, revealing synteny conservation with functional significance.

Kleinjan DA, Seawright A, Elgar G, van Heyningen V. Kleinjan DA, et al. Mamm Genome. 2002 Feb;13(2):102-7. doi: 10.1007/s00335-001-3058-y. Mamm Genome. 2002. PMID: 11889558

4

Conserved elements in Pax6 intron 7 involved in (auto)regulation and alternative transcription.

Kleinjan DA, Seawright A, Childs AJ, van Heyningen V. Kleinjan DA, et al. Dev Biol. 2004 Jan 15;265(2):462-77. doi: 10.1016/j.ydbio.2003.09.011. Dev Biol. 2004. PMID: 14732405 Free article.

5

Long-range control of gene expression: emerging mechanisms and disruption in disease.

Kleinjan DA, van Heyningen V. Kleinjan DA, et al. Am J Hum Genet. 2005 Jan;76(1):8-32. doi: 10.1086/426833. Epub 2004 Nov 17. Am J Hum Genet. 2005. PMID: 15549674 Free PMC article. Review.

6

Functional conservation of Pax6 regulatory elements in humans and mice demonstrated with a novel transgenic reporter mouse.

Tyas DA, Simpson TI, Carr CB, Kleinjan DA, van Heyningen V, Mason JO, Price DJ. Tyas DA, et al. Among authors: kleinjan da. BMC Dev Biol. 2006 May 4;6:21. doi: 10.1186/1471-213X-6-21. BMC Dev Biol. 2006. PMID: 16674807 Free PMC article.

7

Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization.

Manuel M, Georgala PA, Carr CB, Chanas S, Kleinjan DA, Martynoga B, Mason JO, Molinek M, Pinson J, Pratt T, Quinn JC, Simpson TI, Tyas DA, van Heyningen V, West JD, Price DJ. Manuel M, et al. Among authors: kleinjan da. Development. 2007 Feb;134(3):545-55. doi: 10.1242/dev.02764. Epub 2007 Jan 3. Development. 2007. PMID: 17202185 Free PMC article.

8

Subfunctionalization of duplicated zebrafish pax6 genes by cis-regulatory divergence.

Kleinjan DA, Bancewicz RM, Gautier P, Dahm R, Schonthaler HB, Damante G, Seawright A, Hever AM, Yeyati PL, van Heyningen V, Coutinho P. Kleinjan DA, et al. PLoS Genet. 2008 Feb;4(2):e29. doi: 10.1371/journal.pgen.0040029. PLoS Genet. 2008. PMID: 18282108 Free PMC article.

9

Discovery and assessment of conserved Pax6 target genes and enhancers.

Coutinho P, Pavlou S, Bhatia S, Chalmers KJ, Kleinjan DA, van Heyningen V. Coutinho P, et al. Among authors: kleinjan da. Genome Res. 2011 Aug;21(8):1349-59. doi: 10.1101/gr.124115.111. Epub 2011 May 26. Genome Res. 2011. PMID: 21617155 Free PMC article.

10

DNaseI hypersensitivity and ultraconservation reveal novel, interdependent long-range enhancers at the complex Pax6 cis-regulatory region.

McBride DJ, Buckle A, van Heyningen V, Kleinjan DA. McBride DJ, et al. Among authors: kleinjan da. PLoS One. 2011;6(12):e28616. doi: 10.1371/journal.pone.0028616. Epub 2011 Dec 29. PLoS One. 2011. PMID: 22220192 Free PMC article.

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