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Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells.
Lin J, Yang Q, Yan Z, Markowitz J, Wilder PT, Carrier F, Weber DJ. Lin J, et al. J Biol Chem. 2004 Aug 6;279(32):34071-7. doi: 10.1074/jbc.M405419200. Epub 2004 Jun 3. J Biol Chem. 2004. PMID: 15178678 Free article.
This result implicates S100B in the down-regulation of p53 and is consistent with the large decreases in p53 protein levels observed previously in transient co-transfections of p53 and S100B (Lin, J., Blake, M., Tang, C., Zimmer, D., Rustandi, R. R., Weber, D. J …
This result implicates S100B in the down-regulation of p53 and is consistent with the large decreases in p53 protein levels observed previou …
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