Lynch DR - Search Results

1

Cytosolic catechols inhibit alpha-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates.

Mazzulli JR, Mishizen AJ, Giasson BI, Lynch DR, Thomas SA, Nakashima A, Nagatsu T, Ota A, Ischiropoulos H. Mazzulli JR, et al. Among authors: lynch dr. J Neurosci. 2006 Sep 27;26(39):10068-78. doi: 10.1523/JNEUROSCI.0896-06.2006. J Neurosci. 2006. PMID: 17005870 Free PMC article.

2

Distinct cleavage patterns of normal and pathologic forms of alpha-synuclein by calpain I in vitro.

Mishizen-Eberz AJ, Guttmann RP, Giasson BI, Day GA 3rd, Hodara R, Ischiropoulos H, Lee VM, Trojanowski JQ, Lynch DR. Mishizen-Eberz AJ, et al. Among authors: lynch dr. J Neurochem. 2003 Aug;86(4):836-47. doi: 10.1046/j.1471-4159.2003.01878.x. J Neurochem. 2003. PMID: 12887682 Free article.

3

Selective activation induced cleavage of the NR2B subunit by calpain.

Simpkins KL, Guttmann RP, Dong Y, Chen Z, Sokol S, Neumar RW, Lynch DR. Simpkins KL, et al. Among authors: lynch dr. J Neurosci. 2003 Dec 10;23(36):11322-31. doi: 10.1523/JNEUROSCI.23-36-11322.2003. J Neurosci. 2003. PMID: 14672996 Free PMC article.

4

Functional consequences of alpha-synuclein tyrosine nitration: diminished binding to lipid vesicles and increased fibril formation.

Hodara R, Norris EH, Giasson BI, Mishizen-Eberz AJ, Lynch DR, Lee VM, Ischiropoulos H. Hodara R, et al. Among authors: lynch dr. J Biol Chem. 2004 Nov 12;279(46):47746-53. doi: 10.1074/jbc.M408906200. Epub 2004 Sep 9. J Biol Chem. 2004. PMID: 15364911 Free article.

5

Interactions of postsynaptic density-95 and the NMDA receptor 2 subunit control calpain-mediated cleavage of the NMDA receptor.

Dong YN, Waxman EA, Lynch DR. Dong YN, et al. Among authors: lynch dr. J Neurosci. 2004 Dec 8;24(49):11035-45. doi: 10.1523/JNEUROSCI.3722-04.2004. J Neurosci. 2004. PMID: 15590920 Free PMC article.

6

The E46K mutation in alpha-synuclein increases amyloid fibril formation.

Greenbaum EA, Graves CL, Mishizen-Eberz AJ, Lupoli MA, Lynch DR, Englander SW, Axelsen PH, Giasson BI. Greenbaum EA, et al. Among authors: lynch dr. J Biol Chem. 2005 Mar 4;280(9):7800-7. doi: 10.1074/jbc.M411638200. Epub 2005 Jan 4. J Biol Chem. 2005. PMID: 15632170 Free article.

7

Cleavage of alpha-synuclein by calpain: potential role in degradation of fibrillized and nitrated species of alpha-synuclein.

Mishizen-Eberz AJ, Norris EH, Giasson BI, Hodara R, Ischiropoulos H, Lee VM, Trojanowski JQ, Lynch DR. Mishizen-Eberz AJ, et al. Among authors: lynch dr. Biochemistry. 2005 May 31;44(21):7818-29. doi: 10.1021/bi047846q. Biochemistry. 2005. PMID: 15909996

8

Human immunodeficiency virus (HIV)-induced neurotoxicity: roles for the NMDA receptor subtypes.

O'Donnell LA, Agrawal A, Jordan-Sciutto KL, Dichter MA, Lynch DR, Kolson DL. O'Donnell LA, et al. Among authors: lynch dr. J Neurosci. 2006 Jan 18;26(3):981-90. doi: 10.1523/JNEUROSCI.4617-05.2006. J Neurosci. 2006. PMID: 16421318 Free PMC article.

9

Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis.

Hughes EG, Peng X, Gleichman AJ, Lai M, Zhou L, Tsou R, Parsons TD, Lynch DR, Dalmau J, Balice-Gordon RJ. Hughes EG, et al. Among authors: lynch dr. J Neurosci. 2010 Apr 28;30(17):5866-75. doi: 10.1523/JNEUROSCI.0167-10.2010. J Neurosci. 2010. PMID: 20427647 Free PMC article.

10

Anti-NMDA receptor encephalitis antibody binding is dependent on amino acid identity of a small region within the GluN1 amino terminal domain.

Gleichman AJ, Spruce LA, Dalmau J, Seeholzer SH, Lynch DR. Gleichman AJ, et al. Among authors: lynch dr. J Neurosci. 2012 Aug 8;32(32):11082-94. doi: 10.1523/JNEUROSCI.0064-12.2012. J Neurosci. 2012. PMID: 22875940 Free PMC article.

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