Beeser A - Search Results

1

The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity.

Thullberg M, Gad A, Beeser A, Chernoff J, Strömblad S. Thullberg M, et al. Among authors: beeser a. Oncogene. 2007 Mar 15;26(12):1820-8. doi: 10.1038/sj.onc.1209983. Epub 2006 Sep 25. Oncogene. 2007. PMID: 17001318

2

Identification of the atypical MAPK Erk3 as a novel substrate for p21-activated kinase (Pak) activity.

De la Mota-Peynado A, Chernoff J, Beeser A. De la Mota-Peynado A, et al. Among authors: beeser a. J Biol Chem. 2011 Apr 15;286(15):13603-11. doi: 10.1074/jbc.M110.181743. Epub 2011 Feb 11. J Biol Chem. 2011. PMID: 21317288 Free PMC article.

3

Role of group A p21-activated kinases in activation of extracellular-regulated kinase by growth factors.

Beeser A, Jaffer ZM, Hofmann C, Chernoff J. Beeser A, et al. J Biol Chem. 2005 Nov 4;280(44):36609-15. doi: 10.1074/jbc.M502306200. Epub 2005 Aug 29. J Biol Chem. 2005. PMID: 16129686 Free article.

4

p21-activated kinase links Rac/Cdc42 signaling to merlin.

Xiao GH, Beeser A, Chernoff J, Testa JR. Xiao GH, et al. Among authors: beeser a. J Biol Chem. 2002 Jan 11;277(2):883-6. doi: 10.1074/jbc.C100553200. Epub 2001 Nov 21. J Biol Chem. 2002. PMID: 11719502 Free article.

5

p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD.

Cotteret S, Jaffer ZM, Beeser A, Chernoff J. Cotteret S, et al. Among authors: beeser a. Mol Cell Biol. 2003 Aug;23(16):5526-39. doi: 10.1128/MCB.23.16.5526-5539.2003. Mol Cell Biol. 2003. PMID: 12897128 Free PMC article.

6

Production and use of a cell permeable inhibitor of group A Paks (TAT-PID) to analyze signal transduction.

Beeser A, Chernoff J. Beeser A, et al. Methods. 2005 Oct;37(2):203-7. doi: 10.1016/j.ymeth.2005.05.017. Methods. 2005. PMID: 16288885

7

An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase.

Deacon SW, Beeser A, Fukui JA, Rennefahrt UE, Myers C, Chernoff J, Peterson JR. Deacon SW, et al. Among authors: beeser a. Chem Biol. 2008 Apr;15(4):322-31. doi: 10.1016/j.chembiol.2008.03.005. Chem Biol. 2008. PMID: 18420139 Free PMC article.

8

Specificity profiling of Pak kinases allows identification of novel phosphorylation sites.

Rennefahrt UE, Deacon SW, Parker SA, Devarajan K, Beeser A, Chernoff J, Knapp S, Turk BE, Peterson JR. Rennefahrt UE, et al. Among authors: beeser a. J Biol Chem. 2007 May 25;282(21):15667-78. doi: 10.1074/jbc.M700253200. Epub 2007 Mar 28. J Biol Chem. 2007. PMID: 17392278 Free article.

9

ArhGAP15, a Rac-specific GTPase-activating protein, plays a dual role in inhibiting small GTPase signaling.

Radu M, Rawat SJ, Beeser A, Iliuk A, Tao WA, Chernoff J. Radu M, et al. Among authors: beeser a. J Biol Chem. 2013 Jul 19;288(29):21117-21125. doi: 10.1074/jbc.M113.459719. Epub 2013 Jun 11. J Biol Chem. 2013. PMID: 23760270 Free PMC article.

10

Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1.

Reynolds LF, de Bettignies C, Norton T, Beeser A, Chernoff J, Tybulewicz VL. Reynolds LF, et al. Among authors: beeser a. J Biol Chem. 2004 Apr 30;279(18):18239-46. doi: 10.1074/jbc.M400257200. Epub 2004 Feb 5. J Biol Chem. 2004. PMID: 14764585 Free article.

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