Kittendorf JD - Search Results

1

Structural basis for macrolactonization by the pikromycin thioesterase.

Akey DL, Kittendorf JD, Giraldes JW, Fecik RA, Sherman DH, Smith JL. Akey DL, et al. Among authors: kittendorf jd. Nat Chem Biol. 2006 Oct;2(10):537-42. doi: 10.1038/nchembio824. Epub 2006 Sep 10. Nat Chem Biol. 2006. PMID: 16969372

2

Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels.

Giraldes JW, Akey DL, Kittendorf JD, Sherman DH, Smith JL, Fecik RA. Giraldes JW, et al. Among authors: kittendorf jd. Nat Chem Biol. 2006 Oct;2(10):531-6. doi: 10.1038/nchembio822. Epub 2006 Sep 10. Nat Chem Biol. 2006. PMID: 16969373

3

Interrogating the molecular basis for multiple macrolactone ring formation by the pikromycin polyketide synthase.

Kittendorf JD, Beck BJ, Buchholz TJ, Seufert W, Sherman DH. Kittendorf JD, et al. Chem Biol. 2007 Aug;14(8):944-54. doi: 10.1016/j.chembiol.2007.07.013. Chem Biol. 2007. PMID: 17719493 Free PMC article.

4

The methymycin/pikromycin pathway: a model for metabolic diversity in natural product biosynthesis.

Kittendorf JD, Sherman DH. Kittendorf JD, et al. Bioorg Med Chem. 2009 Mar 15;17(6):2137-46. doi: 10.1016/j.bmc.2008.10.082. Epub 2008 Nov 5. Bioorg Med Chem. 2009. PMID: 19027305 Free PMC article.

5

Synthesis and biochemical analysis of complex chain-elongation intermediates for interrogation of molecular specificity in the erythromycin and pikromycin polyketide synthases.

Mortison JD, Kittendorf JD, Sherman DH. Mortison JD, et al. Among authors: kittendorf jd. J Am Chem Soc. 2009 Nov 4;131(43):15784-93. doi: 10.1021/ja9060596. J Am Chem Soc. 2009. PMID: 19810731 Free PMC article.

6

Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.

Scaglione JB, Akey DL, Sullivan R, Kittendorf JD, Rath CM, Kim ES, Smith JL, Sherman DH. Scaglione JB, et al. Among authors: kittendorf jd. Angew Chem Int Ed Engl. 2010 Aug 2;49(33):5726-30. doi: 10.1002/anie.201000032. Angew Chem Int Ed Engl. 2010. PMID: 20623733 Free PMC article. No abstract available.

7

Developing tools for engineering hybrid polyketide synthetic pathways.

Kittendorf JD, Sherman DH. Kittendorf JD, et al. Curr Opin Biotechnol. 2006 Dec;17(6):597-605. doi: 10.1016/j.copbio.2006.09.005. Epub 2006 Oct 12. Curr Opin Biotechnol. 2006. PMID: 17046237 Review.

8

Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin.

Hansen DA, Rath CM, Eisman EB, Narayan AR, Kittendorf JD, Mortison JD, Yoon YJ, Sherman DH. Hansen DA, et al. Among authors: kittendorf jd. J Am Chem Soc. 2013 Jul 31;135(30):11232-8. doi: 10.1021/ja404134f. Epub 2013 Jul 18. J Am Chem Soc. 2013. PMID: 23866020 Free PMC article.

9

An essential role for aspartate 264 in catalysis by tRNA-guanine transglycosylase from Escherichia coli.

Kittendorf JD, Sgraja T, Reuter K, Klebe G, Garcia GA. Kittendorf JD, et al. J Biol Chem. 2003 Oct 24;278(43):42369-76. doi: 10.1074/jbc.M304323200. Epub 2003 Aug 8. J Biol Chem. 2003. PMID: 12909636 Free article.

10

Identification of the rate-determining step of tRNA-guanine transglycosylase from Escherichia coli.

Garcia GA, Chervin SM, Kittendorf JD. Garcia GA, et al. Among authors: kittendorf jd. Biochemistry. 2009 Dec 1;48(47):11243-51. doi: 10.1021/bi901501a. Biochemistry. 2009. PMID: 19874048 Free PMC article.

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