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A positron emission tomography microdosing study with a potential antiamyloid drug in healthy volunteers and patients with Alzheimer's disease.
Bauer M, Langer O, Dal-Bianco P, Karch R, Brunner M, Abrahim A, Lanzenberger R, Hofmann A, Joukhadar C, Carminati P, Ghirardi O, Piovesan P, Forloni G, Corrado ME, Lods N, Dudczak R, Auff E, Kletter K, Müller M. Bauer M, et al. Among authors: ghirardi o. Clin Pharmacol Ther. 2006 Sep;80(3):216-27. doi: 10.1016/j.clpt.2006.05.007. Clin Pharmacol Ther. 2006. PMID: 16952488 Clinical Trial.
Olanzapine (LY170053, 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine), but not the novel atypical antipsychotic ST2472 (9-piperazin-1-ylpyrrolo[2,1-b][1,3]benzothiazepine), chronic administration induces weight gain, hyperphagia, and metabolic dysregulation in mice.
Coccurello R, Caprioli A, Conti R, Ghirardi O, Borsini F, Carminati P, Moles A. Coccurello R, et al. Among authors: ghirardi o. J Pharmacol Exp Ther. 2008 Sep;326(3):905-11. doi: 10.1124/jpet.108.137240. Epub 2008 Jun 20. J Pharmacol Exp Ther. 2008. PMID: 18567835
ST 1535: a preferential A2A adenosine receptor antagonist.
Stasi MA, Borsini F, Varani K, Vincenzi F, Di Cesare MA, Minetti P, Ghirardi O, Carminati P. Stasi MA, et al. Among authors: ghirardi o. Int J Neuropsychopharmacol. 2006 Oct;9(5):575-84. doi: 10.1017/S1461145705006188. Epub 2005 Nov 23. Int J Neuropsychopharmacol. 2006. PMID: 16867213 Free article.
ST2472: a new potential antipsychotic with very low liability to induce side-effects.
Stasi MA, Di Serio S, Vertechy M, Schiavone A, Ghirardi O, Minetti P, Campiani G, Borsini F, Carminati P. Stasi MA, et al. Among authors: ghirardi o. Int J Neuropsychopharmacol. 2008 May;11(3):309-19. doi: 10.1017/S146114570700805X. Epub 2007 Oct 10. Int J Neuropsychopharmacol. 2008. PMID: 17925059 Free article.
53 results