Casas J - Search Results

1

Design, synthesis and activity as acid ceramidase inhibitors of 2-oxooctanoyl and N-oleoylethanolamine analogues.

Grijalvo S, Bedia C, Triola G, Casas J, Llebaria A, Teixidó J, Rabal O, Levade T, Delgado A, Fabriàs G. Grijalvo S, et al. Among authors: casas j. Chem Phys Lipids. 2006 Oct;144(1):69-84. doi: 10.1016/j.chemphyslip.2006.07.001. Epub 2006 Aug 7. Chem Phys Lipids. 2006. PMID: 16942762

2

Synthesis and phospholipase C inhibitory activity of D609 diastereomers.

González-Roura A, Casas J, Llebaria A. González-Roura A, et al. Among authors: casas j. Lipids. 2002 Apr;37(4):401-6. doi: 10.1007/s1145-002-0908-0. Lipids. 2002. PMID: 12030321

3

Synthesis of cyclopropene analogues of ceramide and their effect on dihydroceramide desaturase.

Triola G, Fabriàs G, Casas J, Llebaria A. Triola G, et al. Among authors: casas j. J Org Chem. 2003 Dec 26;68(26):9924-32. doi: 10.1021/jo030141u. J Org Chem. 2003. PMID: 14682684

4

Disclosing new inhibitors by finding similarities in three-dimensional active-site architectures of polynuclear zinc phospholipases and aminopeptidases.

González-Roura A, Navarro I, Delgado A, Llebaria A, Casas J. González-Roura A, et al. Among authors: casas j. Angew Chem Int Ed Engl. 2004 Feb 6;43(7):862-5. doi: 10.1002/anie.200352241. Angew Chem Int Ed Engl. 2004. PMID: 14767959 No abstract available.

5

New aminocyclitols as modulators of glucosylceramide metabolism.

Egido-Gabás M, Serrano P, Casas J, Llebaria A, Delgado A. Egido-Gabás M, et al. Among authors: casas j. Org Biomol Chem. 2005 Apr 7;3(7):1195-201. doi: 10.1039/b411473f. Epub 2005 Mar 1. Org Biomol Chem. 2005. PMID: 15785807

6

Analogs of the dihydroceramide desaturase inhibitor GT11 modified at the amide function: synthesis and biological activities.

Bedia C, Triola G, Casas J, Llebaria A, Fabriàs G. Bedia C, et al. Among authors: casas j. Org Biomol Chem. 2005 Oct 21;3(20):3707-12. doi: 10.1039/b510198k. Epub 2005 Sep 8. Org Biomol Chem. 2005. PMID: 16211106

7

Inhibitors of sphingolipid metabolism enzymes.

Delgado A, Casas J, Llebaria A, Abad JL, Fabrias G. Delgado A, et al. Among authors: casas j. Biochim Biophys Acta. 2006 Dec;1758(12):1957-77. doi: 10.1016/j.bbamem.2006.08.017. Epub 2006 Sep 1. Biochim Biophys Acta. 2006. PMID: 17049336 Free article. Review.

8

Solid-phase synthesis of a combinatorial library of dihydroceramide analogues and its activity in human alveolar epithelial cells.

Villorbina G, Canals D, Carde L, Grijalvo S, Pascual R, Rabal O, Teixidó J, Fabriàs G, Llebaria A, Casas J, Delgado A. Villorbina G, et al. Among authors: casas j. Bioorg Med Chem. 2007 Jan 1;15(1):50-62. doi: 10.1016/j.bmc.2006.10.024. Epub 2006 Oct 17. Bioorg Med Chem. 2007. PMID: 17081760

9

Combinatorial approach to N-substituted aminocyclitol libraries by solution-phase parallel synthesis and preliminary evaluation as glucocerebrosidase inhibitors.

Serrano P, Casas J, Zucco M, Emeric G, Egido-Gabás M, Llebaria A, Delgado A. Serrano P, et al. Among authors: casas j. J Comb Chem. 2007 Jan-Feb;9(1):43-52. doi: 10.1021/cc060080o. J Comb Chem. 2007. PMID: 17206831

10

Chemical tools to investigate sphingolipid metabolism and functions.

Delgado A, Casas J, Llebaria A, Abad JL, Fabriás G. Delgado A, et al. Among authors: casas j. ChemMedChem. 2007 May;2(5):580-606. doi: 10.1002/cmdc.200600195. ChemMedChem. 2007. PMID: 17252619 Review.

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