Mahlert C - Search Results

1

Chemoenzymatic design of acidic lipopeptide hybrids: new insights into the structure-activity relationship of daptomycin and A54145.

Kopp F, Grünewald J, Mahlert C, Marahiel MA. Kopp F, et al. Among authors: mahlert c. Biochemistry. 2006 Sep 5;45(35):10474-81. doi: 10.1021/bi0609422. Biochemistry. 2006. PMID: 16939199

2

Synthesis and derivatization of daptomycin: a chemoenzymatic route to acidic lipopeptide antibiotics.

Grünewald J, Sieber SA, Mahlert C, Linne U, Marahiel MA. Grünewald J, et al. Among authors: mahlert c. J Am Chem Soc. 2004 Dec 29;126(51):17025-31. doi: 10.1021/ja045455t. J Am Chem Soc. 2004. PMID: 15612741

3

Synthesis of linear gramicidin requires the cooperation of two independent reductases.

Schracke N, Linne U, Mahlert C, Marahiel MA. Schracke N, et al. Among authors: mahlert c. Biochemistry. 2005 Jun 14;44(23):8507-13. doi: 10.1021/bi050074t. Biochemistry. 2005. PMID: 15938641

4

Chemoenzymatic approach to enantiopure streptogramin B variants: characterization of stereoselective pristinamycin I cyclase from Streptomyces pristinaespiralis.

Mahlert C, Sieber SA, Grünewald J, Marahiel MA. Mahlert C, et al. J Am Chem Soc. 2005 Jul 6;127(26):9571-80. doi: 10.1021/ja051254t. J Am Chem Soc. 2005. PMID: 15984884

5

Fluorescence resonance energy transfer as a probe of peptide cyclization catalyzed by nonribosomal thioesterase domains.

Grünewald J, Kopp F, Mahlert C, Linne U, Sieber SA, Marahiel MA. Grünewald J, et al. Among authors: mahlert c. Chem Biol. 2005 Aug;12(8):873-81. doi: 10.1016/j.chembiol.2005.05.019. Chem Biol. 2005. PMID: 16125099

6

Peptide macrocyclization: the reductase of the nostocyclopeptide synthetase triggers the self-assembly of a macrocyclic imine.

Kopp F, Mahlert C, Grünewald J, Marahiel MA. Kopp F, et al. Among authors: mahlert c. J Am Chem Soc. 2006 Dec 27;128(51):16478-9. doi: 10.1021/ja0667458. J Am Chem Soc. 2006. PMID: 17177378

7

Mechanistic and structural basis of stereospecific Cbeta-hydroxylation in calcium-dependent antibiotic, a daptomycin-type lipopeptide.

Strieker M, Kopp F, Mahlert C, Essen LO, Marahiel MA. Strieker M, et al. Among authors: mahlert c. ACS Chem Biol. 2007 Mar 20;2(3):187-96. doi: 10.1021/cb700012y. ACS Chem Biol. 2007. PMID: 17373765

8

Stereospecific enzymatic transformation of alpha-ketoglutarate to (2S,3R)-3-methyl glutamate during acidic lipopeptide biosynthesis.

Mahlert C, Kopp F, Thirlway J, Micklefield J, Marahiel MA. Mahlert C, et al. J Am Chem Soc. 2007 Oct 3;129(39):12011-8. doi: 10.1021/ja074427i. Epub 2007 Sep 5. J Am Chem Soc. 2007. PMID: 17784761

9

The iterative gramicidin s thioesterase catalyzes peptide ligation and cyclization.

Hoyer KM, Mahlert C, Marahiel MA. Hoyer KM, et al. Among authors: mahlert c. Chem Biol. 2007 Jan;14(1):13-22. doi: 10.1016/j.chembiol.2006.10.011. Chem Biol. 2007. PMID: 17254948 Free PMC article.

10

In vitro sortagging of an antibody fab fragment: overcoming unproductive reactions of sortase with water and lysine side chains.

Möhlmann S, Mahlert C, Greven S, Scholz P, Harrenga A. Möhlmann S, et al. Among authors: mahlert c. Chembiochem. 2011 Jul 25;12(11):1774-80. doi: 10.1002/cbic.201100002. Epub 2011 Jun 7. Chembiochem. 2011. PMID: 21656631

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