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Enhancing the anti-lymphoma potential of 3,4-methylenedioxymethamphetamine ('ecstasy') through iterative chemical redesign: mechanisms and pathways to cell death.
Wasik AM, Gandy MN, McIldowie M, Holder MJ, Chamba A, Challa A, Lewis KD, Young SP, Scheel-Toellner D, Dyer MJ, Barnes NM, Piggott MJ, Gordon J. Wasik AM, et al. Among authors: dyer mj. Invest New Drugs. 2012 Aug;30(4):1471-83. doi: 10.1007/s10637-011-9730-5. Epub 2011 Aug 18. Invest New Drugs. 2012. PMID: 21850491
Enhanced activation of an amino-terminally truncated isoform of the voltage-gated proton channel HVCN1 enriched in malignant B cells.
Hondares E, Brown MA, Musset B, Morgan D, Cherny VV, Taubert C, Bhamrah MK, Coe D, Marelli-Berg F, Gribben JG, Dyer MJ, DeCoursey TE, Capasso M. Hondares E, et al. Among authors: dyer mj. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):18078-83. doi: 10.1073/pnas.1411390111. Epub 2014 Nov 25. Proc Natl Acad Sci U S A. 2014. PMID: 25425665 Free PMC article.
Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells.
Bellodi C, Lidonnici MR, Hamilton A, Helgason GV, Soliera AR, Ronchetti M, Galavotti S, Young KW, Selmi T, Yacobi R, Van Etten RA, Donato N, Hunter A, Dinsdale D, Tirrò E, Vigneri P, Nicotera P, Dyer MJ, Holyoake T, Salomoni P, Calabretta B. Bellodi C, et al. Among authors: dyer mj. J Clin Invest. 2009 May;119(5):1109-23. doi: 10.1172/JCI35660. Epub 2009 Apr 13. J Clin Invest. 2009. PMID: 19363292 Free PMC article.
318 results