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Page 1
Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development.
Scherer S, Oberle SG, Kanev K, Gerullis AK, Wu M, de Almeida GP, Puleston DJ, Baixauli F, Aly L, Greco A, Nizharadze T, Becker NB, Hoesslin MV, Donhauser LV, Berner J, Chu T, McNamara HA, Esencan Z, Roelli P, Wurmser C, Kleiter I, Vehreschild MJGT, Mayer CA, Knolle P, Klingenspor M, Fumagalli V, Iannacone M, Prlic M, Korn T, Pearce EL, Höfer T, Schulz AM, Zehn D. Scherer S, et al. Among authors: iannacone m. Nat Immunol. 2023 Mar;24(3):501-515. doi: 10.1038/s41590-023-01436-x. Epub 2023 Feb 16. Nat Immunol. 2023. PMID: 36797499
Efficacy of mucosal vaccination using a protozoan parasite as a vehicle for antigen delivery: IgG and neutralizing response after rectal administration of LeCoVax-2, a candidate vaccine against COVID-19.
Epis S, Varotto-Boccazzi I, Manenti A, Rubolini D, Gabrieli P, Cattaneo GM, Gourlay L, Dapporto F, Monti M, Razzano I, Leonardi M, Iannacone M, Recordati C, Bertola L, Fiorina P, Marvasi L, Montomoli E, Zuccotti G, Bandi C. Epis S, et al. Among authors: iannacone m. Pharmacol Res. 2022 Dec;186:106546. doi: 10.1016/j.phrs.2022.106546. Epub 2022 Nov 4. Pharmacol Res. 2022. PMID: 36336215 Free PMC article.
The guanine nucleotide exchange factor Rin-like controls Tfh cell differentiation via CD28 signaling.
Sandner L, Alteneder M, Rica R, Woller B, Sala E, Frey T, Tosevska A, Zhu C, Madern M, Khan M, Hoffmann P, Schebesta A, Taniuchi I, Bonelli M, Schmetterer K, Iannacone M, Kuka M, Ellmeier W, Sakaguchi S, Herbst R, Boucheron N. Sandner L, et al. Among authors: iannacone m. J Exp Med. 2023 Nov 6;220(11):e20221466. doi: 10.1084/jem.20221466. Epub 2023 Sep 13. J Exp Med. 2023. PMID: 37703004 Free PMC article.
Immunomodulatory leptin receptor+ sympathetic perineurial barrier cells protect against obesity by facilitating brown adipose tissue thermogenesis.
Haberman ER, Sarker G, Arús BA, Ziegler KA, Meunier S, Martínez-Sánchez N, Freibergerová E, Yilmaz-Özcan S, Fernández-González I, Zentai C, O'Brien CJO, Grainger DE, Sidarta-Oliveira D, Chakarov S, Raimondi A, Iannacone M, Engelhardt S, López M, Ginhoux F, Domingos AI. Haberman ER, et al. Among authors: iannacone m. Immunity. 2024 Jan 9;57(1):141-152.e5. doi: 10.1016/j.immuni.2023.11.006. Epub 2023 Dec 12. Immunity. 2024. PMID: 38091996
B cell class switch recombination is regulated by DYRK1A through MSH6 phosphorylation.
Stoler-Barak L, Harris E, Peres A, Hezroni H, Kuka M, Di Lucia P, Grenov A, Gurwicz N, Kupervaser M, Yip BH, Iannacone M, Yaari G, Crispino JD, Shulman Z. Stoler-Barak L, et al. Among authors: iannacone m. Nat Commun. 2023 Mar 16;14(1):1462. doi: 10.1038/s41467-023-37205-5. Nat Commun. 2023. PMID: 36927854 Free PMC article.
Immunogenicity and pre-clinical efficacy of an OMV-based SARS-CoV-2 vaccine.
Grandi A, Tomasi M, Ullah I, Bertelli C, Vanzo T, Accordini S, Gagliardi A, Zanella I, Benedet M, Corbellari R, Lascio GD, Tamburini S, Caproni E, Croia L, Ravà M, Fumagalli V, Lucia PD, Marotta D, Sala E, Iannacone M, Kumar P, Mothes W, Uchil PD, Cherepanov P, Bolognesi M, Pizzato M, Grandi G. Grandi A, et al. Among authors: iannacone m. Res Sq [Preprint]. 2023 May 25:rs.3.rs-2788726. doi: 10.21203/rs.3.rs-2788726/v1. Res Sq. 2023. Update in: Vaccines (Basel). 2023 Sep 29;11(10):1546. doi: 10.3390/vaccines11101546 PMID: 37292970 Free PMC article. Updated. Preprint.
Inhibition of the lysine demethylase LSD1 modulates the balance between inflammatory and antiviral responses against coronaviruses.
Mazzarella L, Santoro F, Ravasio R, Fumagalli V, Massa PE, Rodighiero S, Gavilán E, Romanenghi M, Duso BA, Bonetti E, Manganaro L, Pallavi R, Trastulli D, Pallavicini I, Gentile C, Monzani S, Leonardi T, Pasqualato S, Buttinelli G, Di Martino A, Fedele G, Schiavoni I, Stefanelli P, Meroni G, de Francesco R, Steinkuhler C, Fossati G, Iannacone M, Minucci S, Pelicci PG. Mazzarella L, et al. Among authors: iannacone m. Sci Signal. 2023 Dec 19;16(816):eade0326. doi: 10.1126/scisignal.ade0326. Epub 2023 Dec 19. Sci Signal. 2023. PMID: 38113337
HMGB1 is an endogenous immune adjuvant released by necrotic cells.
Rovere-Querini P, Capobianco A, Scaffidi P, Valentinis B, Catalanotti F, Giazzon M, Dumitriu IE, Müller S, Iannacone M, Traversari C, Bianchi ME, Manfredi AA. Rovere-Querini P, et al. Among authors: iannacone m. EMBO Rep. 2004 Aug;5(8):825-30. doi: 10.1038/sj.embor.7400205. Epub 2004 Jul 23. EMBO Rep. 2004. PMID: 15272298 Free PMC article.
158 results