Rognan D - Search Results

1

N1-Benzoyl-N2-[1-(1-naphthyl)ethyl]-trans-1,2-diaminocyclohexanes: Development of 4-chlorophenylcarboxamide (calhex 231) as a new calcium sensing receptor ligand demonstrating potent calcilytic activity.

Kessler A, Faure H, Petrel C, Rognan D, Césario M, Ruat M, Dauban P, Dodd RH. Kessler A, et al. Among authors: rognan d. J Med Chem. 2006 Aug 24;49(17):5119-28. doi: 10.1021/jm051233+. J Med Chem. 2006. PMID: 16913701

2

Protein Structure-Based Organic Chemistry-Driven Ligand Design from Ultralarge Chemical Spaces.

Sindt F, Seyller A, Eguida M, Rognan D. Sindt F, et al. Among authors: rognan d. ACS Cent Sci. 2024 Feb 13;10(3):615-627. doi: 10.1021/acscentsci.3c01521. eCollection 2024 Mar 27. ACS Cent Sci. 2024. PMID: 38559302 Free PMC article.

3

Modeling and mutagenesis of the binding site of Calhex 231, a novel negative allosteric modulator of the extracellular Ca(2+)-sensing receptor.

Petrel C, Kessler A, Maslah F, Dauban P, Dodd RH, Rognan D, Ruat M. Petrel C, et al. Among authors: rognan d. J Biol Chem. 2003 Dec 5;278(49):49487-94. doi: 10.1074/jbc.M308010200. Epub 2003 Sep 23. J Biol Chem. 2003. PMID: 14506236 Free article.

4

Positive and negative allosteric modulators of the Ca2+-sensing receptor interact within overlapping but not identical binding sites in the transmembrane domain.

Petrel C, Kessler A, Dauban P, Dodd RH, Rognan D, Ruat M. Petrel C, et al. Among authors: rognan d. J Biol Chem. 2004 Apr 30;279(18):18990-7. doi: 10.1074/jbc.M400724200. Epub 2004 Feb 19. J Biol Chem. 2004. PMID: 14976203 Free article.

5

Functional characterization of sonic hedgehog mutations associated with holoprosencephaly.

Traiffort E, Dubourg C, Faure H, Rognan D, Odent S, Durou MR, David V, Ruat M. Traiffort E, et al. Among authors: rognan d. J Biol Chem. 2004 Oct 8;279(41):42889-97. doi: 10.1074/jbc.M405161200. Epub 2004 Jul 28. J Biol Chem. 2004. PMID: 15292211 Free article.

6

Synthesis of (+/-)-2-O-[4'-(N-9''-purinyl)butyl] myo-inositol 1,4,5-tris(phosphate), a potent full agonist at the D-myo-inositol 1,4,5-tris(phosphate) receptor.

Moris MA, Caron AZ, Guillemette G, Rognan D, Schmitt M, Schlewer G. Moris MA, et al. Among authors: rognan d. J Med Chem. 2005 Feb 24;48(4):1251-5. doi: 10.1021/jm049458s. J Med Chem. 2005. PMID: 15715492

7

Delineating a Ca2+ binding pocket within the venus flytrap module of the human calcium-sensing receptor.

Silve C, Petrel C, Leroy C, Bruel H, Mallet E, Rognan D, Ruat M. Silve C, et al. Among authors: rognan d. J Biol Chem. 2005 Nov 11;280(45):37917-23. doi: 10.1074/jbc.M506263200. Epub 2005 Sep 7. J Biol Chem. 2005. PMID: 16147994 Free article.

8

In silico-guided target identification of a scaffold-focused library: 1,3,5-triazepan-2,6-diones as novel phospholipase A2 inhibitors.

Muller P, Lena G, Boilard E, Bezzine S, Lambeau G, Guichard G, Rognan D. Muller P, et al. Among authors: rognan d. J Med Chem. 2006 Nov 16;49(23):6768-78. doi: 10.1021/jm0606589. J Med Chem. 2006. PMID: 17154507

9

Selective structure-based virtual screening for full and partial agonists of the beta2 adrenergic receptor.

de Graaf C, Rognan D. de Graaf C, et al. Among authors: rognan d. J Med Chem. 2008 Aug 28;51(16):4978-85. doi: 10.1021/jm800710x. Epub 2008 Aug 5. J Med Chem. 2008. PMID: 18680279

10

Molecular determinants of non-competitive antagonist binding to the mouse GPRC6A receptor.

Faure H, Gorojankina T, Rice N, Dauban P, Dodd RH, Bräuner-Osborne H, Rognan D, Ruat M. Faure H, et al. Among authors: rognan d. Cell Calcium. 2009 Nov-Dec;46(5-6):323-32. doi: 10.1016/j.ceca.2009.09.004. Cell Calcium. 2009. PMID: 19836834

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