Reed MJ - Search Results

1

Focused libraries of 16-substituted estrone derivatives and modified e-ring steroids: inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Vicker N, Lawrence HR, Allan GM, Bubert C, Smith A, Tutill HJ, Purohit A, Day JM, Mahon MF, Reed MJ, Potter BV. Vicker N, et al. Among authors: reed mj. ChemMedChem. 2006 Apr;1(4):464-81. doi: 10.1002/cmdc.200500087. ChemMedChem. 2006. PMID: 16892382

2

D-ring modified estrone derivatives as novel potent inhibitors of steroid sulfatase.

Fischer DS, Woo LW, Mahon MF, Purohit A, Reed MJ, Potter BV. Fischer DS, et al. Among authors: reed mj. Bioorg Med Chem. 2003 Apr 17;11(8):1685-700. doi: 10.1016/s0968-0896(03)00042-7. Bioorg Med Chem. 2003. PMID: 12659755

3

Novel D-ring modified steroid derivatives as potent, non-estrogenic, steroid sulfatase inhibitors with in vivo activity.

Fischer DS, Chander SK, Woo LW, Fenton JC, Purohit A, Reed MJ, Potter BV. Fischer DS, et al. Among authors: reed mj. J Steroid Biochem Mol Biol. 2003 Feb;84(2-3):343-9. doi: 10.1016/s0960-0760(03)00048-7. J Steroid Biochem Mol Biol. 2003. PMID: 12711021

4

A novel 18 beta-glycyrrhetinic acid analogue as a potent and selective inhibitor of 11 beta-hydroxysteroid dehydrogenase 2.

Vicker N, Su X, Lawrence H, Cruttenden A, Purohit A, Reed MJ, Potter BV. Vicker N, et al. Among authors: reed mj. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3263-7. doi: 10.1016/j.bmcl.2004.03.107. Bioorg Med Chem Lett. 2004. PMID: 15149687

5

Novel 18beta-glycyrrhetinic acid analogues as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenases.

Su X, Lawrence H, Ganeshapillai D, Cruttenden A, Purohit A, Reed MJ, Vicker N, Potter BV. Su X, et al. Among authors: reed mj. Bioorg Med Chem. 2004 Aug 15;12(16):4439-57. doi: 10.1016/j.bmc.2004.06.008. Bioorg Med Chem. 2004. PMID: 15265495

6

Novel and potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitors.

Lawrence HR, Vicker N, Allan GM, Smith A, Mahon MF, Tutill HJ, Purohit A, Reed MJ, Potter BV. Lawrence HR, et al. Among authors: reed mj. J Med Chem. 2005 Apr 21;48(8):2759-62. doi: 10.1021/jm049045r. J Med Chem. 2005. PMID: 15828812

7

E-ring modified steroids as novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Fischer DS, Allan GM, Bubert C, Vicker N, Smith A, Tutill HJ, Purohit A, Wood L, Packham G, Mahon MF, Reed MJ, Potter BV. Fischer DS, et al. Among authors: reed mj. J Med Chem. 2005 Sep 8;48(18):5749-70. doi: 10.1021/jm050348a. J Med Chem. 2005. PMID: 16134943

8

Benzothiazole derivatives as novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.

Su X, Vicker N, Ganeshapillai D, Smith A, Purohit A, Reed MJ, Potter BV. Su X, et al. Among authors: reed mj. Mol Cell Endocrinol. 2006 Mar 27;248(1-2):214-7. doi: 10.1016/j.mce.2005.10.022. Epub 2005 Dec 1. Mol Cell Endocrinol. 2006. PMID: 16325333

9

Novel, potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Allan GM, Bubert C, Vicker N, Smith A, Tutill HJ, Purohit A, Reed MJ, Potter BV. Allan GM, et al. Among authors: reed mj. Mol Cell Endocrinol. 2006 Mar 27;248(1-2):204-7. doi: 10.1016/j.mce.2005.10.021. Epub 2005 Dec 7. Mol Cell Endocrinol. 2006. PMID: 16337736

10

Modification of estrone at the 6, 16, and 17 positions: novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Allan GM, Lawrence HR, Cornet J, Bubert C, Fischer DS, Vicker N, Smith A, Tutill HJ, Purohit A, Day JM, Mahon MF, Reed MJ, Potter BV. Allan GM, et al. Among authors: reed mj. J Med Chem. 2006 Feb 23;49(4):1325-45. doi: 10.1021/jm050830t. J Med Chem. 2006. PMID: 16480268

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