Zeng C - Search Results

1

Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis.

Zhou D, Chu W, Rothfuss J, Zeng C, Xu J, Jones L, Welch MJ, Mach RH. Zhou D, et al. Among authors: zeng c. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5041-6. doi: 10.1016/j.bmcl.2006.07.045. Epub 2006 Aug 7. Bioorg Med Chem Lett. 2006. PMID: 16891117

2

N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies.

Chu W, Zhang J, Zeng C, Rothfuss J, Tu Z, Chu Y, Reichert DE, Welch MJ, Mach RH. Chu W, et al. Among authors: zeng c. J Med Chem. 2005 Dec 1;48(24):7637-47. doi: 10.1021/jm0506625. J Med Chem. 2005. PMID: 16302804

3

Synthesis of N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl carbamate analogs as sigma2 receptor ligands.

Vangveravong S, Xu J, Zeng C, Mach RH. Vangveravong S, et al. Among authors: zeng c. Bioorg Med Chem. 2006 Oct 15;14(20):6988-97. doi: 10.1016/j.bmc.2006.06.028. Epub 2006 Jul 11. Bioorg Med Chem. 2006. PMID: 16837201

4

Isatin sulfonamide analogs containing a Michael addition acceptor: a new class of caspase 3/7 inhibitors.

Chu W, Rothfuss J, d'Avignon A, Zeng C, Zhou D, Hotchkiss RS, Mach RH. Chu W, et al. Among authors: zeng c. J Med Chem. 2007 Jul 26;50(15):3751-5. doi: 10.1021/jm070506t. Epub 2007 Jun 23. J Med Chem. 2007. PMID: 17585855

5

Synthesis and structure-activity relationship studies of conformationally flexible tetrahydroisoquinolinyl triazole carboxamide and triazole substituted benzamide analogues as σ2 receptor ligands.

Bai S, Li S, Xu J, Peng X, Sai K, Chu W, Tu Z, Zeng C, Mach RH. Bai S, et al. Among authors: zeng c. J Med Chem. 2014 May 22;57(10):4239-51. doi: 10.1021/jm5001453. Epub 2014 May 12. J Med Chem. 2014. PMID: 24821398 Free PMC article.

6

The σ2 receptor: a novel protein for the imaging and treatment of cancer.

Mach RH, Zeng C, Hawkins WG. Mach RH, et al. Among authors: zeng c. J Med Chem. 2013 Sep 26;56(18):7137-60. doi: 10.1021/jm301545c. Epub 2013 Jun 18. J Med Chem. 2013. PMID: 23734634 Free PMC article. Review.

7

Sigma-2 ligands induce tumour cell death by multiple signalling pathways.

Zeng C, Rothfuss J, Zhang J, Chu W, Vangveravong S, Tu Z, Pan F, Chang KC, Hotchkiss R, Mach RH. Zeng C, et al. Br J Cancer. 2012 Feb 14;106(4):693-701. doi: 10.1038/bjc.2011.602. Epub 2012 Jan 17. Br J Cancer. 2012. PMID: 22251921 Free PMC article.

8

Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site.

Xu J, Zeng C, Chu W, Pan F, Rothfuss JM, Zhang F, Tu Z, Zhou D, Zeng D, Vangveravong S, Johnston F, Spitzer D, Chang KC, Hotchkiss RS, Hawkins WG, Wheeler KT, Mach RH. Xu J, et al. Among authors: zeng c, zeng d. Nat Commun. 2011 Jul 5;2:380. doi: 10.1038/ncomms1386. Nat Commun. 2011. PMID: 21730960 Free PMC article.

9

Characterization and evaluation of two novel fluorescent sigma-2 receptor ligands as proliferation probes.

Zeng C, Vangveravong S, Jones LA, Hyrc K, Chang KC, Xu J, Rothfuss JM, Goldberg MP, Hotchkiss RS, Mach RH. Zeng C, et al. Mol Imaging. 2011 Dec;10(6):420-33. Mol Imaging. 2011. PMID: 22201533 Free PMC article.

10

Functional assays to define agonists and antagonists of the sigma-2 receptor.

Zeng C, Rothfuss JM, Zhang J, Vangveravong S, Chu W, Li S, Tu Z, Xu J, Mach RH. Zeng C, et al. Anal Biochem. 2014 Mar 1;448:68-74. doi: 10.1016/j.ab.2013.12.008. Epub 2013 Dec 12. Anal Biochem. 2014. PMID: 24333652 Free PMC article.

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