Springer TA - Search Results

1

Identification and characterization of a human monoclonal antagonistic antibody AL-57 that preferentially binds the high-affinity form of lymphocyte function-associated antigen-1.

Huang L, Shimaoka M, Rondon IJ, Roy I, Chang Q, Po M, Dransfield DT, Ladner RC, Edge AS, Salas A, Wood CR, Springer TA, Cohen EH. Huang L, et al. Among authors: springer ta. J Leukoc Biol. 2006 Oct;80(4):905-14. doi: 10.1189/jlb.1105649. Epub 2006 Aug 3. J Leukoc Biol. 2006. PMID: 16888085 Free PMC article.

2

Activation of lymphocyte function-associated molecule-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) mimicked by an antibody directed against CD18.

Petruzzelli L, Maduzia L, Springer TA. Petruzzelli L, et al. Among authors: springer ta. J Immunol. 1995 Jul 15;155(2):854-66. J Immunol. 1995. PMID: 7608563

3

Cloning and expression of the chicken CD18 cDNA.

Bilsland CA, Springer TA. Bilsland CA, et al. Among authors: springer ta. J Leukoc Biol. 1994 Apr;55(4):501-6. doi: 10.1002/jlb.55.4.501. J Leukoc Biol. 1994. PMID: 7908319

4

Location of the domains of ICAM-1 by immunolabeling and single-molecule electron microscopy.

Kirchhausen T, Staunton DE, Springer TA. Kirchhausen T, et al. Among authors: springer ta. J Leukoc Biol. 1993 Mar;53(3):342-6. doi: 10.1002/jlb.53.3.342. J Leukoc Biol. 1993. PMID: 8095966

5

Role of ICAM-1 and ICAM-2 and alternate CD11/CD18 ligands in neutrophil transendothelial migration.

Issekutz AC, Rowter D, Springer TA. Issekutz AC, et al. Among authors: springer ta. J Leukoc Biol. 1999 Jan;65(1):117-26. doi: 10.1002/jlb.65.1.117. J Leukoc Biol. 1999. PMID: 9886254

6

Lymphocyte function-associated antigen-1 binding residues in intercellular adhesion molecule-2 (ICAM-2) and the integrin binding surface in the ICAM subfamily.

Casasnovas JM, Pieroni C, Springer TA. Casasnovas JM, et al. Among authors: springer ta. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3017-22. doi: 10.1073/pnas.96.6.3017. Proc Natl Acad Sci U S A. 1999. PMID: 10077629 Free PMC article.

7

Computational design of an integrin I domain stabilized in the open high affinity conformation.

Shimaoka M, Shifman JM, Jing H, Takagi J, Mayo SL, Springer TA. Shimaoka M, et al. Among authors: springer ta. Nat Struct Biol. 2000 Aug;7(8):674-8. doi: 10.1038/77978. Nat Struct Biol. 2000. PMID: 10932253

8

An isolated, surface-expressed I domain of the integrin alphaLbeta2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond.

Lu C, Shimaoka M, Ferzly M, Oxvig C, Takagi J, Springer TA. Lu C, et al. Among authors: springer ta. Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2387-92. doi: 10.1073/pnas.041606398. Proc Natl Acad Sci U S A. 2001. PMID: 11226249 Free PMC article.

9

Locking in alternate conformations of the integrin alphaLbeta2 I domain with disulfide bonds reveals functional relationships among integrin domains.

Lu C, Shimaoka M, Zang Q, Takagi J, Springer TA. Lu C, et al. Among authors: springer ta. Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2393-8. doi: 10.1073/pnas.041618598. Proc Natl Acad Sci U S A. 2001. PMID: 11226250 Free PMC article.

10

Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin alphaL I domains with high affinity and antagonist activity in vivo.

Shimaoka M, Lu C, Palframan RT, von Andrian UH, McCormack A, Takagi J, Springer TA. Shimaoka M, et al. Among authors: springer ta. Proc Natl Acad Sci U S A. 2001 May 22;98(11):6009-14. doi: 10.1073/pnas.101130498. Epub 2001 May 15. Proc Natl Acad Sci U S A. 2001. PMID: 11353828 Free PMC article.

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