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Page 1
Novel 1,3-dicarbonyl compounds having 2(3H)-benzazolonic heterocycles as PPARgamma agonists.
Blanc-Delmas E, Lebegue N, Wallez V, Leclerc V, Yous S, Carato P, Farce A, Bennejean C, Renard P, Caignard DH, Audinot-Bouchez V, Chomarat P, Boutin J, Hennuyer N, Louche K, Carmona MC, Staels B, Pénicaud L, Casteilla L, Lonchampt M, Dacquet C, Chavatte P, Berthelot P, Lesieur D. Blanc-Delmas E, et al. Among authors: louche k. Bioorg Med Chem. 2006 Nov 15;14(22):7377-91. doi: 10.1016/j.bmc.2006.07.029. Epub 2006 Aug 2. Bioorg Med Chem. 2006. PMID: 16887353
S 26948: a new specific peroxisome proliferator activated receptor gamma modulator with potent antidiabetes and antiatherogenic effects.
Carmona MC, Louche K, Lefebvre B, Pilon A, Hennuyer N, Audinot-Bouchez V, Fievet C, Torpier G, Formstecher P, Renard P, Lefebvre P, Dacquet C, Staels B, Casteilla L, Pénicaud L; Consortium of the French Ministry of Research and Technology. Carmona MC, et al. Among authors: louche k. Diabetes. 2007 Nov;56(11):2797-808. doi: 10.2337/db06-1734. Epub 2007 Aug 17. Diabetes. 2007. PMID: 17704298
Fenofibrate prevents Rosiglitazone-induced body weight gain in ob/ob mice.
Carmona MC, Louche K, Nibbelink M, Prunet B, Bross A, Desbazeille M, Dacquet C, Renard P, Casteilla L, Pénicaud L. Carmona MC, et al. Among authors: louche k. Int J Obes (Lond). 2005 Jul;29(7):864-71. doi: 10.1038/sj.ijo.0802943. Int J Obes (Lond). 2005. PMID: 15917863
Coadministration of coenzyme Q prevents rosiglitazone-induced adipogenesis in ob/ob mice.
Carmona MC, Lefebvre P, Lefebvre B, Galinier A, Benani A, Jeanson Y, Louche K, Flajollet S, Ktorza A, Dacquet C, Pénicaud L, Casteilla L; Consortium of the French Ministry of Research and Technology: 'Molecules and New Therapeutic Targets'. Carmona MC, et al. Among authors: louche k. Int J Obes (Lond). 2009 Feb;33(2):204-11. doi: 10.1038/ijo.2008.265. Epub 2009 Jan 6. Int J Obes (Lond). 2009. PMID: 19125161
Browning of white adipose cells by intermediate metabolites: an adaptive mechanism to alleviate redox pressure.
Carrière A, Jeanson Y, Berger-Müller S, André M, Chenouard V, Arnaud E, Barreau C, Walther R, Galinier A, Wdziekonski B, Villageois P, Louche K, Collas P, Moro C, Dani C, Villarroya F, Casteilla L. Carrière A, et al. Among authors: louche k. Diabetes. 2014 Oct;63(10):3253-65. doi: 10.2337/db13-1885. Epub 2014 May 1. Diabetes. 2014. PMID: 24789919
Transient Receptor Potential Canonical 3 (TRPC3) Channels Are Required for Hypothalamic Glucose Detection and Energy Homeostasis.
Chrétien C, Fenech C, Liénard F, Grall S, Chevalier C, Chaudy S, Brenachot X, Berges R, Louche K, Stark R, Nédélec E, Laderrière A, Andrews ZB, Benani A, Flockerzi V, Gascuel J, Hartmann J, Moro C, Birnbaumer L, Leloup C, Pénicaud L, Fioramonti X. Chrétien C, et al. Among authors: louche k. Diabetes. 2017 Feb;66(2):314-324. doi: 10.2337/db16-1114. Epub 2016 Nov 29. Diabetes. 2017. PMID: 27899482
Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass.
Girousse A, Tavernier G, Valle C, Moro C, Mejhert N, Dinel AL, Houssier M, Roussel B, Besse-Patin A, Combes M, Mir L, Monbrun L, Bézaire V, Prunet-Marcassus B, Waget A, Vila I, Caspar-Bauguil S, Louche K, Marques MA, Mairal A, Renoud ML, Galitzky J, Holm C, Mouisel E, Thalamas C, Viguerie N, Sulpice T, Burcelin R, Arner P, Langin D. Girousse A, et al. Among authors: louche k. PLoS Biol. 2013;11(2):e1001485. doi: 10.1371/journal.pbio.1001485. Epub 2013 Feb 19. PLoS Biol. 2013. PMID: 23431266 Free PMC article. Clinical Trial.
26 results