Gélinas C - Search Results

1

Epstein-Barr virus nuclear antigen 2 trans-activates the cellular antiapoptotic bfl-1 gene by a CBF1/RBPJ kappa-dependent pathway.

Pegman PM, Smith SM, D'Souza BN, Loughran ST, Maier S, Kempkes B, Cahill PA, Simmons MJ, Gélinas C, Walls D. Pegman PM, et al. Among authors: gelinas c. J Virol. 2006 Aug;80(16):8133-44. doi: 10.1128/JVI.00278-06. J Virol. 2006. PMID: 16873269 Free PMC article.

Virol. 74:6652-6658, 2000), and the EBV latent membrane protein 1 (LMP1) and its cellular functional homologue CD40 can both drive bfl-1 via an NF-kappaB-dependent enhancer element in the bfl-1 promoter (B. N. D'Souza, L. C. Edelstein, P. M. Pegman, S. M. Smith, S. T. Loug …

Virol. 74:6652-6658, 2000), and the EBV latent membrane protein 1 (LMP1) and its cellular functional homologue CD40 can both drive bfl-1 via …

2

Nuclear factor kappa B-dependent activation of the antiapoptotic bfl-1 gene by the Epstein-Barr virus latent membrane protein 1 and activated CD40 receptor.

D'Souza BN, Edelstein LC, Pegman PM, Smith SM, Loughran ST, Clarke A, Mehl A, Rowe M, Gélinas C, Walls D. D'Souza BN, et al. Among authors: gelinas c. J Virol. 2004 Feb;78(4):1800-16. doi: 10.1128/jvi.78.4.1800-1816.2004. J Virol. 2004. PMID: 14747545 Free PMC article.

3

NF-kappa B-dependent assembly of an enhanceosome-like complex on the promoter region of apoptosis inhibitor Bfl-1/A1.

Edelstein LC, Lagos L, Simmons M, Tirumalai H, Gélinas C. Edelstein LC, et al. Among authors: gelinas c. Mol Cell Biol. 2003 Apr;23(8):2749-61. doi: 10.1128/MCB.23.8.2749-2761.2003. Mol Cell Biol. 2003. PMID: 12665576 Free PMC article.

4

Defective ubiquitin-mediated degradation of antiapoptotic Bfl-1 predisposes to lymphoma.

Fan G, Simmons MJ, Ge S, Dutta-Simmons J, Kucharczak J, Ron Y, Weissmann D, Chen CC, Mukherjee C, White E, Gélinas C. Fan G, et al. Among authors: gelinas c. Blood. 2010 Apr 29;115(17):3559-69. doi: 10.1182/blood-2009-08-236760. Epub 2010 Feb 25. Blood. 2010. PMID: 20185581 Free PMC article.

5

Constitutive proteasome-mediated turnover of Bfl-1/A1 and its processing in response to TNF receptor activation in FL5.12 pro-B cells convert it into a prodeath factor.

Kucharczak JF, Simmons MJ, Duckett CS, Gélinas C. Kucharczak JF, et al. Among authors: gelinas c. Cell Death Differ. 2005 Sep;12(9):1225-39. doi: 10.1038/sj.cdd.4401684. Cell Death Differ. 2005. PMID: 16094403

6

Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist.

Simmons MJ, Fan G, Zong WX, Degenhardt K, White E, Gélinas C. Simmons MJ, et al. Among authors: gelinas c. Oncogene. 2008 Feb 28;27(10):1421-8. doi: 10.1038/sj.onc.1210771. Epub 2007 Sep 3. Oncogene. 2008. PMID: 17724464 Free PMC article.

7

To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis.

Kucharczak J, Simmons MJ, Fan Y, Gélinas C. Kucharczak J, et al. Among authors: gelinas c. Oncogene. 2003 Dec 8;22(56):8961-82. doi: 10.1038/sj.onc.1207230. Oncogene. 2003. PMID: 14663476 Review.

8

The v-Rel oncoprotein complexes with new Rel- and RelA-related proteins in transformed cells.

Xu X, Gélinas C. Xu X, et al. Among authors: gelinas c. Virology. 1995 Mar 10;207(2):362-8. doi: 10.1006/viro.1995.1095. Virology. 1995. PMID: 7886940 Free article.

9

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis.

Zong WX, Edelstein LC, Chen C, Bash J, Gélinas C. Zong WX, et al. Among authors: gelinas c. Genes Dev. 1999 Feb 15;13(4):382-7. doi: 10.1101/gad.13.4.382. Genes Dev. 1999. PMID: 10049353 Free PMC article.

10

CAPERalpha is a novel Rel-TAD-interacting factor that inhibits lymphocyte transformation by the potent Rel/NF-kappaB oncoprotein v-Rel.

Dutta J, Fan G, Gélinas C. Dutta J, et al. Among authors: gelinas c. J Virol. 2008 Nov;82(21):10792-802. doi: 10.1128/JVI.00903-08. Epub 2008 Aug 27. J Virol. 2008. PMID: 18753212 Free PMC article.

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