The hominoid-specific oncogene TBC1D3 activates Ras and modulates epidermal growth factor receptor signaling and trafficking.
Wainszelbaum MJ, Charron AJ, Kong C, Kirkpatrick DS, Srikanth P, Barbieri MA, Gygi SP, Stahl PD.
Wainszelbaum MJ, et al. Among authors: kong c.
J Biol Chem. 2008 May 9;283(19):13233-42. doi: 10.1074/jbc.M800234200. Epub 2008 Mar 4.
J Biol Chem. 2008.
PMID: 18319245
Free PMC article.
Initial work indicates that TBC1D3 is widely expressed in human tissues ( Hodzic, D., Kong, C., Wainszelbaum, M. J., Charron, A. J., Su, X., and Stahl, P. D. (2006) Genomics 88, 731-736 ). ...Moreover, TBC1D3 suppresses polyubiquitination of the EGFR and the recruit …
Initial work indicates that TBC1D3 is widely expressed in human tissues ( Hodzic, D., Kong, C., Wainszelbaum, M. J., Charron, …