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The P2X7 receptor gene polymorphism 1513 A-->C has no effect on clinical prognostic markers, in vitro sensitivity to fludarabine, Bcl-2 family protein expression or survival in B-cell chronic lymphocytic leukaemia.
Starczynski J, Pepper C, Pratt G, Hooper L, Thomas A, Hoy T, Milligan D, Bentley P, Fegan C. Starczynski J, et al. Among authors: fegan c. Br J Haematol. 2003 Oct;123(1):66-71. doi: 10.1046/j.1365-2141.2003.04563.x. Br J Haematol. 2003. PMID: 14510944 Free article.
Results of the MRC pilot study show autografting for younger patients with chronic lymphocytic leukemia is safe and achieves a high percentage of molecular responses.
Milligan DW, Fernandes S, Dasgupta R, Davies FE, Matutes E, Fegan CD, McConkey C, Child JA, Cunningham D, Morgan GJ, Catovsky D; National Cancer Research Institute Haematological Studies Group. Milligan DW, et al. Among authors: fegan cd. Blood. 2005 Jan 1;105(1):397-404. doi: 10.1182/blood-2004-01-0298. Epub 2004 Apr 29. Blood. 2005. PMID: 15117764 Free article. Clinical Trial.
Interaction with vascular endothelium enhances survival in primary chronic lymphocytic leukemia cells via NF-kappaB activation and de novo gene transcription.
Buggins AG, Pepper C, Patten PE, Hewamana S, Gohil S, Moorhead J, Folarin N, Yallop D, Thomas NS, Mufti GJ, Fegan C, Devereux S. Buggins AG, et al. Among authors: fegan c. Cancer Res. 2010 Oct 1;70(19):7523-33. doi: 10.1158/0008-5472.CAN-10-1634. Epub 2010 Aug 24. Cancer Res. 2010. PMID: 20736369
248 results