Gilliland DG - Search Results

1

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

Krivtsov AV, Twomey D, Feng Z, Stubbs MC, Wang Y, Faber J, Levine JE, Wang J, Hahn WC, Gilliland DG, Golub TR, Armstrong SA. Krivtsov AV, et al. Among authors: gilliland dg. Nature. 2006 Aug 17;442(7104):818-22. doi: 10.1038/nature04980. Epub 2006 Jul 16. Nature. 2006. PMID: 16862118

2

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.

Barbie DA, Tamayo P, Boehm JS, Kim SY, Moody SE, Dunn IF, Schinzel AC, Sandy P, Meylan E, Scholl C, Fröhling S, Chan EM, Sos ML, Michel K, Mermel C, Silver SJ, Weir BA, Reiling JH, Sheng Q, Gupta PB, Wadlow RC, Le H, Hoersch S, Wittner BS, Ramaswamy S, Livingston DM, Sabatini DM, Meyerson M, Thomas RK, Lander ES, Mesirov JP, Root DE, Gilliland DG, Jacks T, Hahn WC. Barbie DA, et al. Among authors: gilliland dg. Nature. 2009 Nov 5;462(7269):108-12. doi: 10.1038/nature08460. Epub 2009 Oct 21. Nature. 2009. PMID: 19847166 Free PMC article.

3

Differential niche and Wnt requirements during acute myeloid leukemia progression.

Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DA. Lane SW, et al. Among authors: gilliland dg. Blood. 2011 Sep 8;118(10):2849-56. doi: 10.1182/blood-2011-03-345165. Epub 2011 Jul 15. Blood. 2011. PMID: 21765021 Free PMC article.

4

Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.

Hartwell KA, Miller PG, Mukherjee S, Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M, Järås M, Puram R, Dancik V, Al-Shahrour F, Kindler T, Tothova Z, Chattopadhyay S, Hasaka T, Narayan R, Dai M, Huang C, Shterental S, Chu LP, Haydu JE, Shieh JH, Steensma DP, Munoz B, Bittker JA, Shamji AF, Clemons PA, Tolliday NJ, Carpenter AE, Gilliland DG, Stern AM, Moore MAS, Scadden DT, Schreiber SL, Ebert BL, Golub TR. Hartwell KA, et al. Among authors: gilliland dg. Nat Chem Biol. 2013 Dec;9(12):840-848. doi: 10.1038/nchembio.1367. Epub 2013 Oct 27. Nat Chem Biol. 2013. PMID: 24161946 Free PMC article.

5

Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation.

Golub TR, Barker GF, Lovett M, Gilliland DG. Golub TR, et al. Among authors: gilliland dg. Cell. 1994 Apr 22;77(2):307-16. doi: 10.1016/0092-8674(94)90322-0. Cell. 1994. PMID: 8168137

6

Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells.

Tam WF, Gu TL, Chen J, Lee BH, Bullinger L, Fröhling S, Wang A, Monti S, Golub TR, Gilliland DG. Tam WF, et al. Among authors: gilliland dg. Blood. 2008 Sep 1;112(5):1981-92. doi: 10.1182/blood-2007-07-103010. Epub 2008 Jun 17. Blood. 2008. PMID: 18559972 Free PMC article.

7

Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia.

Ferrando AA, Neuberg DS, Staunton J, Loh ML, Huard C, Raimondi SC, Behm FG, Pui CH, Downing JR, Gilliland DG, Lander ES, Golub TR, Look AT. Ferrando AA, et al. Among authors: gilliland dg. Cancer Cell. 2002 Feb;1(1):75-87. doi: 10.1016/s1535-6108(02)00018-1. Cancer Cell. 2002. PMID: 12086890 Free article.

8

Leukaemia stem cells and the evolution of cancer-stem-cell research.

Huntly BJ, Gilliland DG. Huntly BJ, et al. Among authors: gilliland dg. Nat Rev Cancer. 2005 Apr;5(4):311-21. doi: 10.1038/nrc1592. Nat Rev Cancer. 2005. PMID: 15803157 Review.

9

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress.

Tothova Z, Kollipara R, Huntly BJ, Lee BH, Castrillon DH, Cullen DE, McDowell EP, Lazo-Kallanian S, Williams IR, Sears C, Armstrong SA, Passegué E, DePinho RA, Gilliland DG. Tothova Z, et al. Among authors: gilliland dg. Cell. 2007 Jan 26;128(2):325-39. doi: 10.1016/j.cell.2007.01.003. Cell. 2007. PMID: 17254970 Free article.

10

Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis.

Hofmann I, Stover EH, Cullen DE, Mao J, Morgan KJ, Lee BH, Kharas MG, Miller PG, Cornejo MG, Okabe R, Armstrong SA, Ghilardi N, Gould S, de Sauvage FJ, McMahon AP, Gilliland DG. Hofmann I, et al. Among authors: gilliland dg. Cell Stem Cell. 2009 Jun 5;4(6):559-67. doi: 10.1016/j.stem.2009.03.016. Cell Stem Cell. 2009. PMID: 19497284 Free PMC article.

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