Huang JW - Search Results

1

Development of small-molecule cyclin D1-ablative agents.

Huang JW, Shiau CW, Yang J, Wang DS, Chiu HC, Chen CY, Chen CS. Huang JW, et al. J Med Chem. 2006 Jul 27;49(15):4684-9. doi: 10.1021/jm060057h. J Med Chem. 2006. PMID: 16854074

2

Peroxisome proliferator-activated receptor gamma-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells.

Huang JW, Shiau CW, Yang YT, Kulp SK, Chen KF, Brueggemeier RW, Shapiro CL, Chen CS. Huang JW, et al. Mol Pharmacol. 2005 Apr;67(4):1342-8. doi: 10.1124/mol.104.007732. Epub 2005 Jan 13. Mol Pharmacol. 2005. PMID: 15653552

3

Thiazolidenediones mediate apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functions independently of PPARgamma.

Shiau CW, Yang CC, Kulp SK, Chen KF, Chen CS, Huang JW, Chen CS. Shiau CW, et al. Among authors: huang jw. Cancer Res. 2005 Feb 15;65(4):1561-9. doi: 10.1158/0008-5472.CAN-04-1677. Cancer Res. 2005. PMID: 15735046

4

alpha-Tocopheryl succinate induces apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 function.

Shiau CW, Huang JW, Wang DS, Weng JR, Yang CC, Lin CH, Li C, Chen CS. Shiau CW, et al. Among authors: huang jw. J Biol Chem. 2006 Apr 28;281(17):11819-25. doi: 10.1074/jbc.M511015200. Epub 2006 Mar 6. J Biol Chem. 2006. PMID: 16520381 Free article.

5

From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitors.

Zhu J, Huang JW, Tseng PH, Yang YT, Fowble J, Shiau CW, Shaw YJ, Kulp SK, Chen CS. Zhu J, et al. Among authors: huang jw. Cancer Res. 2004 Jun 15;64(12):4309-18. doi: 10.1158/0008-5472.CAN-03-4063. Cancer Res. 2004. PMID: 15205346

6

Fragment-based design of small molecule X-linked inhibitor of apoptosis protein inhibitors.

Huang JW, Zhang Z, Wu B, Cellitti JF, Zhang X, Dahl R, Shiau CW, Welsh K, Emdadi A, Stebbins JL, Reed JC, Pellecchia M. Huang JW, et al. J Med Chem. 2008 Nov 27;51(22):7111-8. doi: 10.1021/jm8006992. J Med Chem. 2008. PMID: 18956862 Free PMC article.

7

Blockade of STAT3 activation by sorafenib derivatives through enhancing SHP-1 phosphatase activity.

Chen KF, Tai WT, Hsu CY, Huang JW, Liu CY, Chen PJ, Kim I, Shiau CW. Chen KF, et al. Among authors: huang jw. Eur J Med Chem. 2012 Sep;55:220-7. doi: 10.1016/j.ejmech.2012.07.023. Epub 2012 Jul 23. Eur J Med Chem. 2012. PMID: 22871485

8

Development of erlotinib derivatives as CIP2A-ablating agents independent of EGFR activity.

Chen KF, Pao KC, Su JC, Chou YC, Liu CY, Chen HJ, Huang JW, Kim I, Shiau CW. Chen KF, et al. Among authors: huang jw. Bioorg Med Chem. 2012 Oct 15;20(20):6144-53. doi: 10.1016/j.bmc.2012.08.039. Epub 2012 Aug 30. Bioorg Med Chem. 2012. PMID: 22980218

9

Synthesis and biological activity of obatoclax derivatives as novel and potent SHP-1 agonists.

Su JC, Chen KF, Chen WL, Liu CY, Huang JW, Tai WT, Chen PJ, Kim I, Shiau CW. Su JC, et al. Among authors: huang jw. Eur J Med Chem. 2012 Oct;56:127-33. doi: 10.1016/j.ejmech.2012.08.024. Epub 2012 Aug 27. Eur J Med Chem. 2012. PMID: 22982119

10

Sorafenib derivatives induce apoptosis through inhibition of STAT3 independent of Raf.

Chen KF, Tai WT, Huang JW, Hsu CY, Chen WL, Cheng AL, Chen PJ, Shiau CW. Chen KF, et al. Among authors: huang jw. Eur J Med Chem. 2011 Jul;46(7):2845-51. doi: 10.1016/j.ejmech.2011.04.007. Epub 2011 Apr 14. Eur J Med Chem. 2011. PMID: 21531053

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