Dembski MS - Search Results

1

Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90.

Ge J, Normant E, Porter JR, Ali JA, Dembski MS, Gao Y, Georges AT, Grenier L, Pak RH, Patterson J, Sydor JR, Tibbitts TT, Tong JK, Adams J, Palombella VJ. Ge J, et al. Among authors: dembski ms. J Med Chem. 2006 Jul 27;49(15):4606-15. doi: 10.1021/jm0603116. J Med Chem. 2006. PMID: 16854066

2

Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90.

Sydor JR, Normant E, Pien CS, Porter JR, Ge J, Grenier L, Pak RH, Ali JA, Dembski MS, Hudak J, Patterson J, Penders C, Pink M, Read MA, Sang J, Woodward C, Zhang Y, Grayzel DS, Wright J, Barrett JA, Palombella VJ, Adams J, Tong JK. Sydor JR, et al. Among authors: dembski ms. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17408-13. doi: 10.1073/pnas.0608372103. Epub 2006 Nov 7. Proc Natl Acad Sci U S A. 2006. PMID: 17090671 Free PMC article.

3

Dual specificity mitogen-activated protein (MAP) kinase phosphatase-4 plays a potential role in insulin resistance.

Xu H, Dembski M, Yang Q, Yang D, Moriarty A, Tayber O, Chen H, Kapeller R, Tartaglia LA. Xu H, et al. J Biol Chem. 2003 Aug 8;278(32):30187-92. doi: 10.1074/jbc.M302010200. Epub 2003 May 30. J Biol Chem. 2003. PMID: 12777378 Free article.

4

Dual specificity MAPK phosphatase 3 activates PEPCK gene transcription and increases gluconeogenesis in rat hepatoma cells.

Xu H, Yang Q, Shen M, Huang X, Dembski M, Gimeno R, Tartaglia LA, Kapeller R, Wu Z. Xu H, et al. J Biol Chem. 2005 Oct 28;280(43):36013-8. doi: 10.1074/jbc.M508027200. Epub 2005 Aug 26. J Biol Chem. 2005. PMID: 16126724 Free article.

5

Cloning and characterization of an uncoupling protein homolog: a potential molecular mediator of human thermogenesis.

Gimeno RE, Dembski M, Weng X, Deng N, Shyjan AW, Gimeno CJ, Iris F, Ellis SJ, Woolf EA, Tartaglia LA. Gimeno RE, et al. Diabetes. 1997 May;46(5):900-6. doi: 10.2337/diab.46.5.900. Diabetes. 1997. PMID: 9133562

6

Identification and expression cloning of a leptin receptor, OB-R.

Tartaglia LA, Dembski M, Weng X, Deng N, Culpepper J, Devos R, Richards GJ, Campfield LA, Clark FT, Deeds J, Muir C, Sanker S, Moriarty A, Moore KJ, Smutko JS, Mays GG, Wool EA, Monroe CA, Tepper RI. Tartaglia LA, et al. Cell. 1995 Dec 29;83(7):1263-71. doi: 10.1016/0092-8674(95)90151-5. Cell. 1995. PMID: 8548812 Free article.

7

Transport function and regulation of mitochondrial uncoupling proteins 2 and 3.

Jabůrek M, Varecha M, Gimeno RE, Dembski M, Jezek P, Zhang M, Burn P, Tartaglia LA, Garlid KD. Jabůrek M, et al. J Biol Chem. 1999 Sep 10;274(37):26003-7. doi: 10.1074/jbc.274.37.26003. J Biol Chem. 1999. PMID: 10473545 Free article.

8

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors.

Baumann H, Morella KK, White DW, Dembski M, Bailon PS, Kim H, Lai CF, Tartaglia LA. Baumann H, et al. Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8374-8. doi: 10.1073/pnas.93.16.8374. Proc Natl Acad Sci U S A. 1996. PMID: 8710878 Free PMC article.

9

Identification of leptin-induced transcripts in the mouse hypothalamus.

White DW, Zhou J, Stricker-Krongrad A, Ge P, Morgenstern JP, Dembski M, Tartaglia LA. White DW, et al. Diabetes. 2000 Sep;49(9):1443-50. doi: 10.2337/diabetes.49.9.1443. Diabetes. 2000. PMID: 10969827

10

Characterization of the retinoblastoma binding proteins RBP1 and RBP2.

Fattaey AR, Helin K, Dembski MS, Dyson N, Harlow E, Vuocolo GA, Hanobik MG, Haskell KM, Oliff A, Defeo-Jones D, et al. Fattaey AR, et al. Among authors: dembski ms. Oncogene. 1993 Nov;8(11):3149-56. Oncogene. 1993. PMID: 8414517

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