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2,122 results

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Page 1
Discovery and pharmacological evaluation of growth hormone secretagogue receptor antagonists.
Xin Z, Serby MD, Zhao H, Kosogof C, Szczepankiewicz BG, Liu M, Liu B, Hutchins CW, Sarris KA, Hoff ED, Falls HD, Lin CW, Ogiela CA, Collins CA, Brune ME, Bush EN, Droz BA, Fey TA, Knourek-Segel VE, Shapiro R, Jacobson PB, Beno DW, Turner TM, Sham HL, Liu G. Xin Z, et al. Among authors: lin cw. J Med Chem. 2006 Jul 27;49(15):4459-69. doi: 10.1021/jm060461g. J Med Chem. 2006. PMID: 16854051
Optimization of 2,4-diaminopyrimidines as GHS-R antagonists: side chain exploration.
Liu B, Liu M, Xin Z, Zhao H, Serby MD, Kosogof C, Nelson LT, Szczepankiewicz BG, Kaszubska W, Schaefer VG, Falls HD, Lin CW, Collins CA, Sham HL, Liu G. Liu B, et al. Among authors: lin cw. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1864-8. doi: 10.1016/j.bmcl.2006.01.012. Epub 2006 Jan 25. Bioorg Med Chem Lett. 2006. PMID: 16442284
Biaryl amide glucagon receptor antagonists.
Kurukulasuriya R, Sorensen BK, Link JT, Patel JR, Jae HS, Winn MX, Rohde JR, Grihalde ND, Lin CW, Ogiela CA, Adler AL, Collins CA. Kurukulasuriya R, et al. Among authors: lin cw. Bioorg Med Chem Lett. 2004 May 3;14(9):2047-50. doi: 10.1016/j.bmcl.2004.02.056. Bioorg Med Chem Lett. 2004. PMID: 15080976
Nonsteroidal selective glucocorticoid modulators: the effect of C-10 substitution on receptor selectivity and functional potency of 5-allyl-2,5-dihydro-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines.
Kym PR, Kort ME, Coghlan MJ, Moore JL, Tang R, Ratajczyk JD, Larson DP, Elmore SW, Pratt JK, Stashko MA, Falls HD, Lin CW, Nakane M, Miller L, Tyree CM, Miner JN, Jacobson PB, Wilcox DM, Nguyen P, Lane BC. Kym PR, et al. Among authors: lin cw. J Med Chem. 2003 Mar 13;46(6):1016-30. doi: 10.1021/jm020335m. J Med Chem. 2003. PMID: 12620078
Nonsteroidal selective glucocorticoid modulators: the effect of C-5 alkyl substitution on the transcriptional activation/repression profile of 2,5-dihydro-10-methoxy-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines.
Elmore SW, Coghlan MJ, Anderson DD, Pratt JK, Green BE, Wang AX, Stashko MA, Lin CW, Tyree CM, Miner JN, Jacobson PB, Wilcox DM, Lane BC. Elmore SW, et al. Among authors: lin cw. J Med Chem. 2001 Dec 6;44(25):4481-91. doi: 10.1021/jm010367u. J Med Chem. 2001. PMID: 11728194
Synthesis and biological activity of CCK heptapeptide analogues. Effects of conformational constraints and standard modifications on receptor subtype selectivity, functional activity in vitro, and appetite suppression in vivo.
Holladay MW, Bennett MJ, Tufano MD, Lin CW, Asin KE, Witte DG, Miller TR, Bianchi BR, Nikkel AL, Bednarz L, et al. Holladay MW, et al. Among authors: lin cw. J Med Chem. 1992 Aug 7;35(16):2919-28. doi: 10.1021/jm00094a001. J Med Chem. 1992. PMID: 1501220
2,122 results