Ocain T - Search Results

1

Identification of a regulatory autophosphorylation site in the serine-threonine kinase RIP2.

Dorsch M, Wang A, Cheng H, Lu C, Bielecki A, Charron K, Clauser K, Ren H, Polakiewicz RD, Parsons T, Li P, Ocain T, Xu Y. Dorsch M, et al. Among authors: ocain t. Cell Signal. 2006 Dec;18(12):2223-9. doi: 10.1016/j.cellsig.2006.05.005. Epub 2006 May 22. Cell Signal. 2006. PMID: 16824733

2

Participation of Rip2 in lipopolysaccharide signaling is independent of its kinase activity.

Lu C, Wang A, Dorsch M, Tian J, Nagashima K, Coyle AJ, Jaffee B, Ocain TD, Xu Y. Lu C, et al. J Biol Chem. 2005 Apr 22;280(16):16278-83. doi: 10.1074/jbc.M410114200. Epub 2005 Feb 3. J Biol Chem. 2005. PMID: 15691841 Free article.

3

Regulation of IRAK-4 kinase activity via autophosphorylation within its activation loop.

Cheng H, Addona T, Keshishian H, Dahlstrand E, Lu C, Dorsch M, Li Z, Wang A, Ocain TD, Li P, Parsons TF, Jaffee B, Xu Y. Cheng H, et al. Among authors: ocain td. Biochem Biophys Res Commun. 2007 Jan 19;352(3):609-16. doi: 10.1016/j.bbrc.2006.11.068. Epub 2006 Nov 21. Biochem Biophys Res Commun. 2007. PMID: 17141195

4

Nucleotide binding to CARD12 and its role in CARD12-mediated caspase-1 activation.

Lu C, Wang A, Wang L, Dorsch M, Ocain TD, Xu Y. Lu C, et al. Biochem Biophys Res Commun. 2005 Jun 17;331(4):1114-9. doi: 10.1016/j.bbrc.2005.04.027. Biochem Biophys Res Commun. 2005. PMID: 15882992

5

A selective small molecule IkappaB Kinase beta inhibitor blocks nuclear factor kappaB-mediated inflammatory responses in human fibroblast-like synoviocytes, chondrocytes, and mast cells.

Wen D, Nong Y, Morgan JG, Gangurde P, Bielecki A, Dasilva J, Keaveney M, Cheng H, Fraser C, Schopf L, Hepperle M, Harriman G, Jaffee BD, Ocain TD, Xu Y. Wen D, et al. J Pharmacol Exp Ther. 2006 Jun;317(3):989-1001. doi: 10.1124/jpet.105.097584. Epub 2006 Mar 8. J Pharmacol Exp Ther. 2006. PMID: 16525037

6

Mice deficient in PKC theta demonstrate impaired in vivo T cell activation and protection from T cell-mediated inflammatory diseases.

Anderson K, Fitzgerald M, Dupont M, Wang T, Paz N, Dorsch M, Healy A, Xu Y, Ocain T, Schopf L, Jaffee B, Picarella D. Anderson K, et al. Among authors: ocain t. Autoimmunity. 2006 Sep;39(6):469-78. doi: 10.1080/08916930600907954. Autoimmunity. 2006. PMID: 17060026 Free article.

7

Rapid TNFR1-dependent lymphocyte depletion in vivo with a selective chemical inhibitor of IKKbeta.

Nagashima K, Sasseville VG, Wen D, Bielecki A, Yang H, Simpson C, Grant E, Hepperle M, Harriman G, Jaffee B, Ocain T, Xu Y, Fraser CC. Nagashima K, et al. Among authors: ocain t. Blood. 2006 Jun 1;107(11):4266-73. doi: 10.1182/blood-2005-09-3852. Epub 2006 Jan 26. Blood. 2006. PMID: 16439676 Free article.

8

Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis.

Izmailova ES, Paz N, Alencar H, Chun M, Schopf L, Hepperle M, Lane JH, Harriman G, Xu Y, Ocain T, Weissleder R, Mahmood U, Healy AM, Jaffee B. Izmailova ES, et al. Among authors: ocain t. Arthritis Rheum. 2007 Jan;56(1):117-28. doi: 10.1002/art.22303. Arthritis Rheum. 2007. PMID: 17195214 Free article.

9

IKKbeta inhibition protects against bone and cartilage destruction in a rat model of rheumatoid arthritis.

Schopf L, Savinainen A, Anderson K, Kujawa J, DuPont M, Silva M, Siebert E, Chandra S, Morgan J, Gangurde P, Wen D, Lane J, Xu Y, Hepperle M, Harriman G, Ocain T, Jaffee B. Schopf L, et al. Among authors: ocain t. Arthritis Rheum. 2006 Oct;54(10):3163-73. doi: 10.1002/art.22081. Arthritis Rheum. 2006. PMID: 17009244 Free article.

10

Pharmacological characterization of guinea pig chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2).

Liu F, Gonzalo JA, Manning S, O'Connell LE, Fedyk ER, Burke KE, Elder AM, Pulido JC, Cao W, Tayber O, Qiu Y, Ghosh S, Ocain TD, Hodge MR, Suzuki-Yagawa Y. Liu F, et al. Prostaglandins Other Lipid Mediat. 2005 May;76(1-4):133-47. doi: 10.1016/j.prostaglandins.2005.03.001. Prostaglandins Other Lipid Mediat. 2005. PMID: 15967168

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